P42229 | STA5A_HUMAN | Signal transducer and activator of transcription 5A (STAT5A)

Helixβ‑strandTurn secondary structure

Pfam Domain Table

AccessionDomainRangeColor
PF00017SH2595–669
PF01017STAT_alpha146–324
PF02864STAT_bind336–469
PF02865STAT_int3–123
PF21354STAT_linker492–574

 3D structures mapped by conservation among orthologs


 [ Alpha Fold Model ] (go)



 Known binders annotated in ChEMBL

 IC50 CSV
Only the first 20 rows are shown.
molecule_chembl_idstructureassay_typerelation valueunitmol_wtsmilesorganism assay_chembl_idbao_label
CHEMBL574058 IC50 = 5.0 nM 429.28 Cc1cc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)ccc1F Homo sapiens CHEMBL3225223 cell-based format
CHEMBL603469 IC50 = 10.0 nM 439.47 C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O Homo sapiens CHEMBL5347064 cell-based format
CHEMBL1231124 IC50 = 41.0 nM 348.77 Cc1cc(Nc2nc(N[C@@H](C)c3ncc(F)cn3)ncc2Cl)[nH]n1 Homo sapiens CHEMBL1656964 cell-based format
CHEMBL559787 IC50 = 689.0 nM 397.43 O=C1NCc2c1c1c3ccccc3n3c1c1c2c2ccccc2n1C[C@@H](O)[C@@H](O)C3 Homo sapiens CHEMBL1053845 cell-based format