3D structures mapped by conservation among orthologs

[ Domain: "Hormone receptor domain (HRM, Pfam 02793)" // HRM ]

 PyMOL session

[ Alpha Fold Model ] (go)

Known binders annotated in ChEMBL

 IC50 CSV

Only the first 20 rows are shown.

molecule_chembl_id	structure	assay_type	relation	value	unit	mol_wt	smiles	organism	assay_chembl_id	bao_label
CHEMBL3927475		IC50	=	206.0	nM	552.65	O=C(N[C@H]1c2ccccc2C[C@H]1O)[C@H](Cc1ccccc1)C[C@H](O)CNS(=O)(=O)c1ccc2c(c1)OCCO2	Homo sapiens	CHEMBL3880376	cell-based format
CHEMBL3986225		IC50	=	280.0	nM	529.06	O=C(N[C@H]1c2ccccc2C[C@H]1O)[C@H](Cc1ccccc1)C[C@H](O)CNS(=O)(=O)c1ccc(Cl)cc1	Homo sapiens	CHEMBL3880376	cell-based format
CHEMBL3973956		IC50	=	426.0	nM	536.65	CC(=O)c1ccc(S(=O)(=O)NC[C@@H](O)C[C@@H](Cc2ccccc2)C(=O)N[C@H]2c3ccccc3C[C@H]2O)cc1	Homo sapiens	CHEMBL3880376	cell-based format