P40925 | MDHC_HUMAN | Malate dehydrogenase, cytoplasmic (MDH1)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
Accession | Domain | Range | Color |
---|---|---|---|
PF00056 | Ldh_1_N | 6–152 | |
PF02866 | Ldh_1_C | 156–330 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
---|---|---|---|---|---|---|---|---|---|---|
CHEMBL4096306 | IC50 | = | 920.0 | nM | 437.54 | C#CCOC(=O)c1ccc(O)c(NC(=O)COc2ccc(C(C)(C)CC(C)(C)C)cc2)c1 | Homo sapiens | CHEMBL4031659 | assay format | |
CHEMBL4068781 | Ki | = | 740.0 | nM | 411.54 | COC(=O)c1cccc(NC(=O)CCOc2ccc(C(C)(C)CC(C)(C)C)cc2)c1 | Homo sapiens | CHEMBL4031687 | assay format |