P40313 | CTRL_HUMAN | Chymotrypsin-like protease CTRL-1 (CTRL)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00089 | Trypsin - Trypsin | 34~257 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL74336 |  |
IC50 | = | 6.0 | nM | 563.74 | CC(C)CC(C=O)NC(=O)C(CCC/N=C(\N)N[N+](=O)[O-])NC(=O)C(CCCCCCCCC#N)C1CCCC1 | Homo sapiens | CHEMBL661257 | assay format |
| CHEMBL1929019 |  |
IC50 | = | 65.0 | nM | 591.71 | CC(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CC1CCCCC1)C(=O)N[C@H](C=O)Cc1c[nH]cn1)C(C)C | Homo sapiens | CHEMBL1932244 | assay format |
| CHEMBL1929023 |  |
IC50 | = | 98.0 | nM | 534.66 | CC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CC1CCCCC1)C(=O)N[C@H](C=O)Cc1c[nH]cn1)C(C)C)[C@@H](C)O | Homo sapiens | CHEMBL1932244 | assay format |
| CHEMBL1929020 |  |
IC50 | = | 270.0 | nM | 504.63 | CC(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CC1CCCCC1)C(=O)N[C@H](C=O)Cc1c[nH]cn1)C(C)C | Homo sapiens | CHEMBL1932244 | assay format |
| CHEMBL1929022 |  |
IC50 | = | 340.0 | nM | 520.63 | CC(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](CC1CCCCC1)C(=O)N[C@H](C=O)Cc1c[nH]cn1)C(C)C | Homo sapiens | CHEMBL1932244 | assay format |
| CHEMBL1929018 |  |
IC50 | = | 390.0 | nM | 585.66 | CC(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C=O)Cc1c[nH]cn1)C(C)C | Homo sapiens | CHEMBL1932244 | assay format |