P39877 | PA2G5_HUMAN | Phospholipase A2 group V (PLA2G5)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00068 | Phospholip_A2_1 - Phospholipase A2 | 22~130 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL5172164 |  |
IC50 | = | 10.0 | nM | 442.47 | Cc1c(C(=O)C(N)=O)c2c(OCC(=O)O)cccn2c1Cc1ccccc1-c1ccccc1 | Homo sapiens | CHEMBL5150982 | cell-based format |
| CHEMBL515637 |  |
IC50 | = | 35.0 | nM | 430.46 | CCc1c(C(=O)C(N)=O)c2c(OCC(=O)O)cc3ccccc3c2n1Cc1ccccc1 | Homo sapiens | CHEMBL990834 | single protein format |
| CHEMBL148649 |  |
IC50 | = | 44.0 | nM | 394.43 | CCc1c(C(=O)C(N)=O)c2c(OC(C)C(=O)O)cccc2n1Cc1ccccc1 | Homo sapiens | CHEMBL990834 | single protein format |
| CHEMBL514692 |  |
IC50 | = | 100.0 | nM | 519.58 | CCc1c(C(=O)C(N)=O)c2c(OCC(=O)NS(=O)(=O)c3ccccc3)cccc2n1Cc1ccccc1 | Homo sapiens | CHEMBL990834 | single protein format |
| CHEMBL332993 |  |
IC50 | = | 100.0 | nM | 456.5 | CCc1c(C(=O)C(N)=O)c2c(OCC(=O)O)cccn2c1Cc1ccccc1-c1ccccc1 | Homo sapiens | CHEMBL990834 | single protein format |
| CHEMBL446349 |  |
IC50 | = | 140.0 | nM | 569.64 | CCc1c(C(=O)C(N)=O)c2c(OCC(=O)NS(=O)(=O)c3ccccc3)cc3ccccc3c2n1Cc1ccccc1 | Homo sapiens | CHEMBL990834 | single protein format |
| CHEMBL4205008 |  |
IC50 | = | 180.0 | nM | 407.35 | CC(Cc1ccnc(-n2c(C(N)=O)cc3ccc(OC(F)(F)F)cc32)c1)C(=O)O | Homo sapiens | CHEMBL4199511 | single protein format |
| CHEMBL357979 |  |
IC50 | = | 270.0 | nM | 442.47 | Cc1c(C(=O)C(N)=O)c2c(OCC(=O)O)cccc2n1Cc1ccccc1-c1ccccc1 | Homo sapiens | CHEMBL917131 | assay format |
| CHEMBL1644549 |  |
IC50 | = | 440.0 | nM | 383.57 | CCCCCCCCCCCCCCC(=O)C(=O)N[C@@H](CC(C)C)C(=O)O | Homo sapiens | CHEMBL1648030 | single protein format |
| CHEMBL148674 |  |
IC50 | = | 500.0 | nM | 380.4 | CCc1c(C(=O)C(N)=O)c2c(OCC(=O)O)cccc2n1Cc1ccccc1 | Homo sapiens | CHEMBL862130 | single protein format |
| CHEMBL208315 |  |
IC50 | = | 500.0 | nM | 394.43 | CCc1c(C(=O)C(N)=O)c2c(OCC(=O)O)cc(C)cc2n1Cc1ccccc1 | Homo sapiens | CHEMBL862130 | single protein format |
| CHEMBL4205511 |  |
IC50 | = | 510.0 | nM | 407.35 | CC(Cc1cccc(-n2c(C(N)=O)cc3ccc(OC(F)(F)F)cc32)n1)C(=O)O | Homo sapiens | CHEMBL4199511 | single protein format |
| CHEMBL4214052 |  |
IC50 | = | 510.0 | nM | 406.36 | CC(Cc1cccc(-n2c(C(N)=O)cc3ccc(OC(F)(F)F)cc32)c1)C(=O)O | Homo sapiens | CHEMBL4199511 | single protein format |
| CHEMBL485601 |  |
IC50 | = | 530.0 | nM | 504.75 | CCCCCCCCCCCC(=O)c1c(O)c(C)c(O)c(C(=O)CCCCCCCCCCC)c1O | Homo sapiens | CHEMBL989794 | single protein format |
| CHEMBL220842 |  |
IC50 | = | 550.0 | nM | 588.87 | CCCCCCCCCCCCCCOC(COCCCCCCCCCC)COc1ccc(-c2noc(=O)[nH]2)cc1 | Homo sapiens | CHEMBL917131 | assay format |
| CHEMBL4213094 |  |
IC50 | = | 720.0 | nM | 393.32 | NC(=O)c1cc2ccc(OC(F)(F)F)cc2n1-c1cc(CCC(=O)O)ccn1 | Homo sapiens | CHEMBL4199511 | single protein format |
| CHEMBL208429 |  |
IC50 | = | 800.0 | nM | 380.4 | Cc1cc(OCC(=O)O)c2c(C(=O)C(N)=O)c(C)n(Cc3ccccc3)c2c1 | Homo sapiens | CHEMBL862130 | single protein format |
| CHEMBL346196 |  |
IC50 | = | 800.0 | nM | 366.37 | Cc1c(C(=O)C(N)=O)c2c(OCC(=O)O)cccc2n1Cc1ccccc1 | Homo sapiens | CHEMBL862130 | single protein format |