P38936 | CDN1A_HUMAN | Cyclin-dependent kinase inhibitor 1 (CDKN1A)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF02234 | CDI - Cyclin-dependent kinase inhibitor | 21~68 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL5277005 |  |
IC50 | = | 170.0 | nM | 317.43 | CC(=O)c1cccc(CC2CCCc3c2[nH]c2ccc(C)cc32)c1 | Homo sapiens | CHEMBL5236830 | single protein format |
| CHEMBL5266126 |  |
IC50 | = | 490.0 | nM | 413.44 | COc1ccc(C(=O)Nc2nc(NC(=O)c3ccccc3)nn2-c2ccccc2)cc1 | Homo sapiens | CHEMBL5236830 | single protein format |
| CHEMBL4226806 |  |
IC50 | = | 640.0 | nM | 274.33 | N#Cc1ccc2ncnc(NCCc3ccccc3)c2c1 | Homo sapiens | CHEMBL4220243 | assay format |
| CHEMBL1434157 |  |
IC50 | = | 760.0 | nM | 404.43 | CCOC(=O)c1ccc(Nc2nc3nonc3nc2Nc2cccc(C)c2C)cc1 | Homo sapiens | CHEMBL5236830 | single protein format |