P38571 | LICH_HUMAN | Lysosomal acid lipase/cholesteryl ester hydrolase (LIPA)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00561 | Abhydrolase_1 - alpha/beta hydrolase fold | 80~380 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL1085463 |  |
IC50 | = | 68.0 | nM | 298.37 | O=C(Oc1nsnc1N1CCCCC1)N1CCOCC1 | Homo sapiens | CHEMBL1119694 | single protein format |
| CHEMBL1085857 |  |
IC50 | = | 152.0 | nM | 296.4 | O=C(Oc1nsnc1N1CCCCC1)N1CCCCC1 | Homo sapiens | CHEMBL1119694 | single protein format |
| CHEMBL1082839 |  |
IC50 | = | 189.0 | nM | 312.4 | O=C(Oc1nsnc1N1CCCCCC1)N1CCOCC1 | Homo sapiens | CHEMBL1119694 | single protein format |
| CHEMBL1082838 |  |
IC50 | = | 300.0 | nM | 310.42 | O=C(Oc1nsnc1N1CCCCCC1)N1CCCCC1 | Homo sapiens | CHEMBL1119694 | single protein format |
| CHEMBL1082517 |  |
IC50 | = | 424.0 | nM | 298.37 | O=C(Oc1nsnc1N1CCOCC1)N1CCCCC1 | Homo sapiens | CHEMBL1119694 | single protein format |
| CHEMBL1085856 |  |
IC50 | = | 473.0 | nM | 284.34 | O=C(Oc1nsnc1N1CCCC1)N1CCOCC1 | Homo sapiens | CHEMBL1119694 | single protein format |
| CHEMBL1082518 |  |
IC50 | = | 492.0 | nM | 300.34 | O=C(Oc1nsnc1N1CCOCC1)N1CCOCC1 | Homo sapiens | CHEMBL1119694 | single protein format |
| CHEMBL1085855 |  |
IC50 | = | 496.0 | nM | 282.37 | O=C(Oc1nsnc1N1CCCC1)N1CCCCC1 | Homo sapiens | CHEMBL1119694 | single protein format |