P35346 | SSR5_HUMAN | Somatostatin receptor type 5 (SSTR5)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00001 | 7tm_1 - 7 transmembrane receptor (rhodopsin family) | 57~304 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3665819 |  |
IC50 | = | 0.129 | nM | 578.64 | CCOc1cc(CN2CCC3(CC2)CN(c2ccc(C(=O)O)c(OC)c2)C(=O)O3)cc(OCC)c1-c1ccc(F)cc1 | Homo sapiens | CHEMBL3705142 | single protein format |
| CHEMBL3665831 |  |
IC50 | = | 0.1523 | nM | 554.57 | CCOc1cc(CN2CCC3(CC2)CN(c2ccc(C(=O)O)cc2)C(=O)O3)c(-c2cc(F)c(F)cc2F)cc1C | Homo sapiens | CHEMBL3705142 | single protein format |
| CHEMBL3665837 |  |
IC50 | = | 0.1645 | nM | 580.48 | O=C(O)c1ccc(N2CC3(CCN(Cc4cc(OC(F)(F)F)ccc4-c4ccc(F)c(F)c4F)CC3)OC2=O)cc1 | Homo sapiens | CHEMBL3705142 | single protein format |
| CHEMBL3665853 |  |
IC50 | = | 0.1715 | nM | 476.53 | COc1cc(CN2CCC3(CC2)CN(c2ccc(C(=O)O)cc2)C(=O)O3)cc2c(OC)cccc12 | Homo sapiens | CHEMBL3705142 | single protein format |
| CHEMBL3665832 |  |
IC50 | = | 0.1881 | nM | 568.59 | CCOc1cc(CN2CCC3(CC2)CN(c2ccc(C(=O)O)c(C)c2)C(=O)O3)c(-c2ccc(F)c(F)c2F)cc1C | Homo sapiens | CHEMBL3705142 | single protein format |
| CHEMBL4287248 |  |
IC50 | = | 0.2 | nM | 553.01 | O=C(O)c1ccc(N2CC3(CCN(Cc4cc(Cl)c(-c5ccc(F)cc5F)c(C5CC5)c4)CC3)OC2=O)cc1 | Homo sapiens | CHEMBL4270312 | cell-based format |
| CHEMBL4293458 |  |
IC50 | = | 0.2 | nM | 577.6 | CC(C)n1cc(CN2CCC3(CC2)CN(c2ccc(C(=O)O)cc2)C(=O)O3)c2c(-c3ccc(F)c(F)c3F)cccc21 | Homo sapiens | CHEMBL4270312 | cell-based format |
| CHEMBL3670748 |  |
IC50 | = | 0.2245 | nM | 553.66 | CC(C)n1cc(CN2CCC3(CC2)CN(c2ccc(C(=O)O)cc2)C(=O)O3)c2c(OCc3ccccc3)cccc21 | Homo sapiens | CHEMBL3705142 | single protein format |
| CHEMBL3665838 |  |
IC50 | = | 0.2277 | nM | 584.59 | CCOc1cc(CN2CCC3(CC2)CN(c2ccc(C(=O)O)c(OC)c2)C(=O)O3)c(-c2ccc(F)c(F)c2F)cc1C | Homo sapiens | CHEMBL3705142 | single protein format |
| CHEMBL3665854 |  |
IC50 | = | 0.2329 | nM | 525.0 | CCOc1cc(CN2CCC3(CC2)CN(c2ccc(C(=O)O)cc2)C(=O)O3)cc2c(OC)ccc(Cl)c12 | Homo sapiens | CHEMBL3705142 | single protein format |
| CHEMBL3665839 |  |
IC50 | = | 0.2432 | nM | 536.55 | O=C(O)c1ccc(N2CC3(CCN(Cc4cc5c(cc4-c4cc(F)c(F)cc4F)CCC5)CC3)OC2=O)cc1 | Homo sapiens | CHEMBL3705142 | single protein format |
| CHEMBL3670744 |  |
IC50 | = | 0.2602 | nM | 554.65 | CC(C)n1nc(CN2CCC3(CC2)CN(c2ccc(C(=O)O)cc2)C(=O)O3)c2cc(OCc3ccccc3)ccc21 | Homo sapiens | CHEMBL3705142 | single protein format |
| CHEMBL3665836 |  |
IC50 | = | 0.2715 | nM | 554.57 | CC(C)Oc1ccc(-c2cc(F)c(F)cc2F)c(CN2CCC3(CC2)CN(c2ccc(C(=O)O)cc2)C(=O)O3)c1 | Homo sapiens | CHEMBL3705142 | single protein format |
| CHEMBL4286244 |  |
IC50 | = | 0.3 | nM | 487.6 | CC(C)n1cc(CN2CCC3(CC2)CN(c2ccc(C(=O)O)cc2)C(=O)O3)c2c(C3CC3)cccc21 | Homo sapiens | CHEMBL4270312 | cell-based format |
| CHEMBL3670725 |  |
IC50 | = | 0.3174 | nM | 464.56 | Cc1cc(CN2CCC3(CC2)CN(c2ccc(C(=O)O)cc2)C(=O)O3)cc2c1OCCC2(C)C | Homo sapiens | CHEMBL3705142 | single protein format |
| CHEMBL3665811 |  |
IC50 | = | 0.3227 | nM | 572.64 | CCOc1cc(CN2CCC3(CC2)CN(c2ccc(-c4nnn[nH]4)cc2)C(=O)O3)cc(OCC)c1-c1ccc(F)cc1 | Homo sapiens | CHEMBL3705142 | single protein format |
| CHEMBL3670754 |  |
IC50 | = | 0.3418 | nM | 577.6 | CC(C)n1cc(CN2CCC3(CC2)CN(c2ccc(C(=O)O)cc2)C(=O)O3)c2cc(-c3ccc(F)c(F)c3F)ccc21 | Homo sapiens | CHEMBL3705142 | single protein format |
| CHEMBL3665818 |  |
IC50 | = | 0.359 | nM | 583.06 | CCOc1cc(CN2CCC3(CC2)CN(c2ccc(C(=O)O)cc2Cl)C(=O)O3)cc(OCC)c1-c1ccc(F)cc1 | Homo sapiens | CHEMBL3705142 | single protein format |
| CHEMBL3665847 |  |
IC50 | = | 0.3946 | nM | 504.59 | CCOc1cc(CN2CCC3(CC2)CN(c2ccc(C(=O)O)cc2)C(=O)O3)c(-n2cc(C)cn2)cc1C | Homo sapiens | CHEMBL3705142 | single protein format |
| CHEMBL3665841 |  |
IC50 | = | 0.3973 | nM | 572.56 | CCOc1cc(CN2CCC3(CC2)CN(c2ccc(C(=O)O)cc2F)C(=O)O3)c(-c2ccc(F)c(F)c2F)cc1C | Homo sapiens | CHEMBL3705142 | single protein format |