P35226 | BMI1_HUMAN | Polycomb complex protein BMI-1 (BMI1)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF13923 | zf-C3HC4_2 | 17–56 | |
| PF16207 | RAWUL | 162–226 |
3D structures mapped by conservation among orthologs
[ Domain: "Ubiquitin-like" // RAWUL_1 ]
[ Domain: "Ubiquitin-like" // RAWUL_2 ]
[ Domain: "RING/U-box" // zf-C3HC4_4 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL5270667 |  |
IC50 | = | 1.0 | nM | 370.34 | Cc1nc2ccccc2n1-c1nncc(Nc2ccc(C(F)(F)F)cc2)n1 | Homo sapiens | CHEMBL5262856 | single protein format |
| CHEMBL5272260 |  |
IC50 | = | 1.0 | nM | 346.39 | CCc1nc2ccccc2n1-c1cnnc(Nc2ccc(OC)cc2)n1 | Homo sapiens | CHEMBL5262856 | single protein format |
| CHEMBL5272817 |  |
IC50 | = | 1.0 | nM | 332.37 | COc1ccc(Nc2nncc(-n3c(C)nc4ccccc43)n2)cc1 | Homo sapiens | CHEMBL5262856 | single protein format |
| CHEMBL5270622 |  |
IC50 | = | 1.0 | nM | 382.37 | CCc1nc2ccccc2n1-c1cnnc(Nc2ccc(OC(F)F)cc2)n1 | Homo sapiens | CHEMBL5262856 | single protein format |
| CHEMBL5266175 |  |
IC50 | = | 1.0 | nM | 368.35 | Cc1nc2ccccc2n1-c1cnnc(Nc2ccc(OC(F)F)cc2)n1 | Homo sapiens | CHEMBL5262856 | single protein format |
| CHEMBL5276953 |  |
IC50 | = | 1.0 | nM | 394.39 | FC(F)Oc1ccc(Nc2nncc(-n3c(C4CC4)nc4ccccc43)n2)cc1 | Homo sapiens | CHEMBL5262856 | single protein format |
| CHEMBL5280041 |  |
IC50 | = | 1.0 | nM | 400.36 | CCc1nc2ccc(F)cc2n1-c1cnnc(Nc2ccc(OC(F)F)cc2)n1 | Homo sapiens | CHEMBL5262856 | single protein format |
| CHEMBL5273906 |  |
IC50 | = | 1.0 | nM | 386.34 | Cc1nc2ccc(F)cc2n1-c1cnnc(Nc2ccc(OC(F)F)cc2)n1 | Homo sapiens | CHEMBL5262856 | single protein format |
| CHEMBL5268696 |  |
IC50 | = | 1.0 | nM | 414.37 | Fc1ccc2nc(C3CC3)n(-c3cnnc(Nc4ccc(C(F)(F)F)cc4)n3)c2c1 | Homo sapiens | CHEMBL5262856 | single protein format |
| CHEMBL5289952 |  |
IC50 | = | 1.0 | nM | 396.38 | FC(F)(F)c1ccc(Nc2nncc(-n3c(C4CC4)nc4ccccc43)n2)cc1 | Homo sapiens | CHEMBL5262856 | single protein format |
| CHEMBL5282609 |  |
IC50 | = | 1.0 | nM | 388.33 | Cc1nc2ccc(F)cc2n1-c1cnnc(Nc2ccc(C(F)(F)F)cc2)n1 | Homo sapiens | CHEMBL5262856 | single protein format |
| CHEMBL5282796 |  |
IC50 | = | 1.0 | nM | 316.37 | Cc1ccc(Nc2nncc(-n3c(C)nc4ccccc43)n2)cc1 | Homo sapiens | CHEMBL5262856 | single protein format |
| CHEMBL5278557 |  |
IC50 | = | 1.0 | nM | 402.36 | CCc1nc2ccc(F)cc2n1-c1cnnc(Nc2ccc(C(F)(F)F)cc2)n1 | Homo sapiens | CHEMBL5262856 | single protein format |
| CHEMBL5274905 |  |
IC50 | = | 1.0 | nM | 370.34 | Cc1nc2ccccc2n1-c1cnnc(Nc2ccc(C(F)(F)F)cc2)n1 | Homo sapiens | CHEMBL5262856 | single protein format |
| CHEMBL5270834 |  |
IC50 | = | 1.0 | nM | 346.39 | CCc1nc2ccccc2n1-c1nncc(Nc2ccc(OC)cc2)n1 | Homo sapiens | CHEMBL5262856 | single protein format |
| CHEMBL5287305 |  |
IC50 | = | 1.0 | nM | 358.41 | COc1ccc(Nc2cnnc(-n3c(C4CC4)nc4ccccc43)n2)cc1 | Homo sapiens | CHEMBL5262856 | single protein format |
| CHEMBL5288239 |  |
IC50 | = | 1.0 | nM | 414.37 | Fc1ccc2nc(C3CC3)n(-c3nncc(Nc4ccc(C(F)(F)F)cc4)n3)c2c1 | Homo sapiens | CHEMBL5262856 | single protein format |
| CHEMBL5281109 |  |
IC50 | = | 1.0 | nM | 402.36 | CCc1nc2ccc(F)cc2n1-c1nncc(Nc2ccc(C(F)(F)F)cc2)n1 | Homo sapiens | CHEMBL5262856 | single protein format |
| CHEMBL5282393 |  |
IC50 | = | 1.0 | nM | 394.39 | FC(F)Oc1ccc(Nc2cnnc(-n3c(C4CC4)nc4ccccc43)n2)cc1 | Homo sapiens | CHEMBL5262856 | single protein format |
| CHEMBL5269901 |  |
IC50 | = | 1.0 | nM | 396.38 | FC(F)(F)c1ccc(Nc2cnnc(-n3c(C4CC4)nc4ccccc43)n2)cc1 | Homo sapiens | CHEMBL5262856 | single protein format |