P34981 | TRFR_HUMAN | Thyrotropin-releasing hormone receptor (TRHR)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00001 | 7tm_1 - 7 transmembrane receptor (rhodopsin family) | 42~320 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL224730 |  |
Ki | = | 3.0 | nM | 514.57 | C[n+]1c[nH]cc1C[C@H](N)C(=O)N1C(=O)CC[C@H]1C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N1CCC[C@H]1C(N)=O | Homo sapiens | CHEMBL917826 | single protein format |
| CHEMBL223972 |  |
Ki | = | 3.2 | nM | 390.44 | Cn1cnc(C[C@H](NC(=O)[C@@H]2CCCC(=O)N2)C(=O)N2CCC[C@H]2C(N)=O)c1 | Homo sapiens | CHEMBL917826 | single protein format |
| CHEMBL390942 |  |
Ki | = | 11.0 | nM | 404.47 | CCn1cnc(C[C@H](NC(=O)[C@@H]2CCCC(=O)N2)C(=O)N2CCC[C@H]2C(N)=O)c1 | Homo sapiens | CHEMBL917826 | single protein format |
| CHEMBL1472 |  |
Ki | = | 20.0 | nM | 362.39 | NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H]1CCC(=O)N1 | Homo sapiens | CHEMBL917826 | single protein format |
| CHEMBL224525 |  |
Ki | = | 400.0 | nM | 418.5 | CCCc1nc(C[C@H](NC(=O)[C@@H]2CCCC(=O)N2)C(=O)N2CCC[C@H]2C(N)=O)c[nH]1 | Homo sapiens | CHEMBL917826 | single protein format |