P34949 | MPI_HUMAN | Mannose-6-phosphate isomerase (MPI)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF01238 | PMI_typeI_C - Phosphomannose isomerase type I C-terminal | 337~381 | |
| PF20511 | PMI_typeI_cat - Phosphomannose isomerase type I, catalytic domain | 6~154 | |
| PF20512 | PMI_typeI_hel - Phosphomannose isomerase type I, helical insertion domain | 170~257 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL51085 |  |
IC50 | = | 190.0 | nM | 274.18 | O=c1c2ccccc2[se]n1-c1ccccc1 | Homo sapiens | CHEMBL1737863 | single protein format |
| CHEMBL1410147 |  |
IC50 | = | 270.0 | nM | 357.4 | O=P(Nc1nccs1)(c1ccccc1)c1nc2ccccc2s1 | Homo sapiens | CHEMBL1737863 | single protein format |
| CHEMBL1978279 |  |
IC50 | < | 391.0 | nM | 279.34 | COc1ccc(/N=C/C2=C(O)c3ccccc3CC2)cc1 | Homo sapiens | CHEMBL1614547 | single protein format |
| CHEMBL1333250 |  |
IC50 | = | 707.0 | nM | 426.48 | O=C(O)c1ccccc1NS(=O)(=O)c1cccc(-n2sc3ccccc3c2=O)c1 | Homo sapiens | CHEMBL1737863 | single protein format |
| CHEMBL1714665 |  |
IC50 | = | 709.0 | nM | 335.27 | O=c1c2c([N+](=O)[O-])cc([N+](=O)[O-])cc2sn1-c1ccc(F)cc1 | Homo sapiens | CHEMBL1737863 | single protein format |
| CHEMBL1993627 |  |
IC50 | = | 828.76 | nM | 293.32 | OC1=C(/C=N/c2ccc3c(c2)OCO3)CCc2ccccc21 | Homo sapiens | CHEMBL1614547 | single protein format |
| CHEMBL1725120 |  |
IC50 | = | 985.0 | nM | 273.33 | Cc1ccc(C)c(-n2sc3cc(F)ccc3c2=O)c1 | Homo sapiens | CHEMBL1737863 | single protein format |
| CHEMBL1314602 |  |
IC50 | = | 1000.0 | nM | 275.3 | COc1ccc(-n2sc3ccc(F)cc3c2=O)cc1 | Homo sapiens | CHEMBL1777059 | single protein format |
| CHEMBL1706034 |  |
IC50 | = | 1000.0 | nM | 275.3 | COc1ccc(-n2sc3cc(F)ccc3c2=O)cc1 | Homo sapiens | CHEMBL3375686 | single protein format |