P32745 | SSR3_HUMAN | Somatostatin receptor type 3 (SSTR3)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00001 | 7tm_1 - 7 transmembrane receptor (rhodopsin family) | 61~313 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3323074 |  |
IC50 | = | 0.64 | nM | 561.62 | CCOC(=O)c1ccnc([C@]2(c3cnn(C)c3)N[C@@H](c3nc(-c4ccc(F)cc4)c[nH]3)Cc3c2[nH]c2ccccc32)c1 | Homo sapiens | CHEMBL3378639 | cell-based format |
| CHEMBL2204935 |  |
IC50 | = | 0.66 | nM | 494.53 | Cc1nc([C@]2(c3cnn(C)c3)N[C@@H](c3nc(-c4ccc(F)cc4)c[nH]3)Cc3c2[nH]c2ccccc32)no1 | Homo sapiens | CHEMBL2210526 | cell-based format |
| CHEMBL2204939 |  |
IC50 | = | 0.74 | nM | 492.56 | Cn1cc(C2(c3cnn(C)c3)N[C@@H](c3nc(-c4ccc(F)cc4)c[nH]3)Cc3c2[nH]c2ccccc32)cn1 | Homo sapiens | CHEMBL2210526 | cell-based format |
| CHEMBL2204934 |  |
IC50 | = | 0.76 | nM | 484.58 | Fc1ccc(-c2c[nH]c([C@H]3Cc4c([nH]c5ccccc45)C(c4ccccc4)(c4ccccc4)N3)n2)cc1 | Homo sapiens | CHEMBL2210526 | cell-based format |
| CHEMBL3323076 |  |
IC50 | = | 0.78 | nM | 561.62 | CCOC(=O)c1cncc([C@]2(c3cnn(C)c3)N[C@@H](c3nc(-c4ccc(F)cc4)c[nH]3)Cc3c2[nH]c2ccccc32)c1 | Homo sapiens | CHEMBL3378639 | cell-based format |
| CHEMBL2069500 |  |
IC50 | = | 0.8 | nM | 396.54 | c1ccc(-c2c[nH]c([C@H]3Cc4c([nH]c5ccccc45)C(C4CCCCC4)N3)n2)cc1 | Homo sapiens | CHEMBL2072489 | cell-based format |
| CHEMBL3323072 |  |
IC50 | = | 0.83 | nM | 561.62 | CCOC(=O)c1cccc([C@]2(c3cnn(C)c3)N[C@@H](c3nc(-c4ccc(F)cc4)c[nH]3)Cc3c2[nH]c2ccccc32)n1 | Homo sapiens | CHEMBL3378639 | cell-based format |
| CHEMBL2204938 |  |
IC50 | = | 0.94 | nM | 494.53 | Cc1nc([C@]2(c3cnn(C)c3)N[C@H](c3nc(-c4ccc(F)cc4)c[nH]3)Cc3c2[nH]c2ccccc32)no1 | Homo sapiens | CHEMBL2210526 | cell-based format |
| CHEMBL2204940 |  |
IC50 | = | 0.97 | nM | 496.51 | Cc1nc(C2(c3noc(C)n3)N[C@@H](c3nc(-c4ccc(F)cc4)c[nH]3)Cc3c2[nH]c2ccccc32)no1 | Homo sapiens | CHEMBL2210526 | cell-based format |
| CHEMBL3582321 |  |
IC50 | = | 1.1 | nM | 535.59 | Cc1nc([C@]2(c3cnn(CC4CC4)c3)N[C@@H](c3nc(-c4ccc(F)cn4)c[nH]3)Cc3c2[nH]c2ccccc32)no1 | Homo sapiens | CHEMBL3583381 | cell-based format |
| CHEMBL2204936 |  |
IC50 | = | 1.1 | nM | 494.53 | Cc1nc([C@@]2(c3cnn(C)c3)N[C@@H](c3nc(-c4ccc(F)cc4)c[nH]3)Cc3c2[nH]c2ccccc32)no1 | Homo sapiens | CHEMBL2210526 | cell-based format |
| CHEMBL3680938 |  |
IC50 | = | 1.2 | nM | 539.62 | COC1CC2C(C1)C2C1(c2nnc(C)o2)N[C@@H](c2nc(-c3ccc(F)c(C)n3)c[nH]2)Cc2c1[nH]c1ccccc21 | Homo sapiens | CHEMBL3705198 | cell-based format |
| CHEMBL3323084 |  |
IC50 | = | 1.22 | nM | 533.57 | Cn1cc([C@@]2(c3cncc(C(=O)O)c3)N[C@@H](c3nc(-c4ccc(F)cc4)c[nH]3)Cc3c2[nH]c2ccccc32)cn1 | Homo sapiens | CHEMBL3378639 | cell-based format |
| CHEMBL3775042 |  |
IC50 | = | 1.4 | nM | 476.54 | Cc1nc([C@]2(c3cnn(C)c3)N[C@@H](c3nc(-c4ccccc4)c[nH]3)Cc3c2[nH]c2ccccc32)no1 | Homo sapiens | CHEMBL3779603 | single protein format |
| CHEMBL3582341 |  |
IC50 | = | 1.4 | nM | 565.61 | CCn1cc([C@@]2(c3nn(CC4CC4)c(=O)o3)N[C@@H](c3nc(-c4ccc(F)cn4)c[nH]3)Cc3c2[nH]c2ccccc32)cn1 | Homo sapiens | CHEMBL3583381 | cell-based format |
| CHEMBL3323073 |  |
IC50 | = | 1.52 | nM | 561.62 | CCOC(=O)c1cccc([C@@]2(c3cnn(C)c3)N[C@@H](c3nc(-c4ccc(F)cc4)c[nH]3)Cc3c2[nH]c2ccccc32)n1 | Homo sapiens | CHEMBL3378639 | cell-based format |
| CHEMBL3680937 |  |
IC50 | = | 1.7 | nM | 513.58 | Cc1nnc(C2(C3CCCCO3)N[C@@H](c3nc(-c4ccc(F)c(C)n4)c[nH]3)Cc3c2[nH]c2ccccc32)o1 | Homo sapiens | CHEMBL3705198 | cell-based format |
| CHEMBL2069505 |  |
IC50 | = | 1.7 | nM | 414.58 | c1ccc(-c2c[nH]c([C@H]3Cc4c([nH]c5ccccc45)C(C4CCSCC4)N3)n2)cc1 | Homo sapiens | CHEMBL2072489 | cell-based format |
| CHEMBL3323078 |  |
IC50 | = | 1.72 | nM | 561.62 | CCOC(=O)c1ccc([C@]2(c3cnn(C)c3)N[C@@H](c3nc(-c4ccc(F)cc4)c[nH]3)Cc3c2[nH]c2ccccc32)nc1 | Homo sapiens | CHEMBL3378639 | cell-based format |
| CHEMBL3775532 |  |
IC50 | = | 1.8 | nM | 434.49 | Fc1ccc(-c2c[nH]c([C@H]3Cc4c([nH]c5ccccc45)[C@@H](C4CCOCC4)N3)n2)cc1F | Homo sapiens | CHEMBL3779603 | single protein format |