P30838 | AL3A1_HUMAN | Aldehyde dehydrogenase, dimeric NADP-preferring (ALDH3A1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00171 | Aldedh - Aldehyde dehydrogenase family | 3~425 |
3D structures mapped by conservation among orthologs
[ Domain: "ALDH-like" // Aldedh_2nd ]
[ Domain: "ALDH-like" // Aldedh_1st_1 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4745360 |  |
IC50 | = | 193.0 | nM | 564.1 | Br.N=C(N)SCc1ccc(CN2C(=O)C(=O)c3cc(Br)cc(Br)c32)cc1 | Homo sapiens | CHEMBL4708028 | single protein format |
| CHEMBL1378094 |  |
IC50 | = | 200.0 | nM | 290.32 | Cc1nc2ccccc2n1S(=O)(=O)c1ccc(F)cc1 | Homo sapiens | CHEMBL3118331 | single protein format |
| CHEMBL4754311 |  |
IC50 | = | 219.0 | nM | 503.19 | Br.N=C(N)SCc1ccc(CN2C(=O)C(=O)c3cc(F)cc(Br)c32)cc1 | Homo sapiens | CHEMBL4708028 | single protein format |
| CHEMBL4777582 |  |
IC50 | = | 219.0 | nM | 475.2 | Br.N=C(N)SCc1ccc(CN2C(=O)C(=O)c3cc(Cl)cc(Cl)c32)cc1 | Homo sapiens | CHEMBL4708028 | single protein format |
| CHEMBL4753971 |  |
IC50 | = | 241.0 | nM | 424.3 | Br.N=C(N)SCc1ccc(CN2C(=O)C(=O)c3cccc(F)c32)cc1 | Homo sapiens | CHEMBL4708028 | single protein format |
| CHEMBL4791741 |  |
IC50 | = | 246.0 | nM | 471.19 | Br.N=C(N)[Se]Cc1ccc(CN2C(=O)C(=O)c3cccc(F)c32)cc1 | Homo sapiens | CHEMBL4708028 | single protein format |
| CHEMBL4755837 |  |
IC50 | = | 246.0 | nM | 474.3 | Br.N=C(N)SCc1ccc(CN2C(=O)C(=O)c3cccc(C(F)(F)F)c32)cc1 | Homo sapiens | CHEMBL4708028 | single protein format |
| CHEMBL4763602 |  |
IC50 | = | 251.0 | nM | 521.2 | Br.N=C(N)[Se]Cc1ccc(CN2C(=O)C(=O)c3cccc(C(F)(F)F)c32)cc1 | Homo sapiens | CHEMBL4708028 | single protein format |
| CHEMBL3112681 |  |
IC50 | = | 300.0 | nM | 306.77 | Cc1nc2ccccc2n1S(=O)(=O)c1ccc(Cl)cc1 | Homo sapiens | CHEMBL3118331 | single protein format |
| CHEMBL3128211 |  |
IC50 | = | 300.0 | nM | 379.42 | O=C1C(=O)N(CN2CCN(Cc3ccc4c(c3)OCO4)CC2)c2ccccc21 | Homo sapiens | CHEMBL3130564 | assay format |
| CHEMBL1453099 |  |
IC50 | = | 310.0 | nM | 263.3 | O=C1C(=O)N(C/C=C/c2ccccc2)c2ccccc21 | Homo sapiens | CHEMBL3130564 | assay format |
| CHEMBL4752256 |  |
IC50 | = | 327.0 | nM | 522.09 | Br.N=C(N)[Se]Cc1ccc(CN2C(=O)C(=O)c3cc(Cl)cc(Cl)c32)cc1 | Homo sapiens | CHEMBL4708028 | single protein format |
| CHEMBL4755996 |  |
IC50 | = | 344.0 | nM | 532.09 | Br.N=C(N)[Se]Cc1ccc(CN2C(=O)C(=O)c3cc(Br)ccc32)cc1 | Homo sapiens | CHEMBL4708028 | single protein format |
| CHEMBL4742685 |  |
IC50 | = | 360.0 | nM | 474.3 | Br.N=C(N)SCc1ccc(CN2C(=O)C(=O)c3cc(C(F)(F)F)ccc32)cc1 | Homo sapiens | CHEMBL4708028 | single protein format |
| CHEMBL3128208 |  |
IC50 | = | 360.0 | nM | 240.06 | Cc1cc(Br)c2c(c1)C(=O)C(=O)N2 | Homo sapiens | CHEMBL3130564 | assay format |
| CHEMBL4764389 |  |
IC50 | = | 368.0 | nM | 550.08 | Br.N=C(N)[Se]Cc1ccc(CN2C(=O)C(=O)c3cc(F)cc(Br)c32)cc1 | Homo sapiens | CHEMBL4708028 | single protein format |
| CHEMBL3128209 |  |
IC50 | = | 420.0 | nM | 217.27 | CCCCCN1C(=O)C(=O)c2ccccc21 | Homo sapiens | CHEMBL3130564 | assay format |
| CHEMBL3128205 |  |
IC50 | = | 450.0 | nM | 251.28 | O=C1C(=O)N(CCc2ccccc2)c2ccccc21 | Homo sapiens | CHEMBL3130564 | assay format |
| CHEMBL1328547 |  |
IC50 | = | 460.0 | nM | 265.31 | O=C1C(=O)N(CCCc2ccccc2)c2ccccc21 | Homo sapiens | CHEMBL3130564 | assay format |
| CHEMBL1411903 |  |
IC50 | = | 700.0 | nM | 286.36 | Cc1ccc(S(=O)(=O)n2c(C)nc3ccccc32)cc1 | Homo sapiens | CHEMBL3118331 | single protein format |