P28562 | DUS1_HUMAN | Dual specificity protein phosphatase 1 (DUSP1)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00581 | Rhodanese | 13–130 | |
| PF00782 | DSPc | 181–311 |
3D structures mapped by conservation among orthologs
[ Domain: "DnaD domain" // DSPc ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL584481 |  |
IC50 | = | 520.0 | nM | 595.7 | O=C1/C(=C/c2cn(-c3ccccc3)nc2-c2ccc(OCc3ccccc3F)cc2)SC(=S)N1CCS(=O)(=O)O | Homo sapiens | CHEMBL1047961 | single protein format |
| CHEMBL565810 |  |
IC50 | = | 780.0 | nM | 577.71 | O=C1/C(=C/c2cn(-c3ccccc3)nc2-c2ccc(OCc3ccccc3)cc2)SC(=S)N1CCS(=O)(=O)O | Homo sapiens | CHEMBL1047961 | single protein format |