P28161 | GSTM2_HUMAN | Glutathione S-transferase Mu 2 (GSTM2)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00043 | GST_C - Glutathione S-transferase, C-terminal domain | 104~191 | |
| PF02798 | GST_N - Glutathione S-transferase, N-terminal domain | 3~82 |
3D structures mapped by conservation among orthologs
[ Domain: "Glutathione S-transferase (GST)-C" // GST_C_3 ]
[ Domain: "Thioredoxin-like" // GST_N_5 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3360522 |  |
IC50 | = | 3.0 | nM | 436.45 | O=C(NOCc1ccccc1)c1ccc(CSc2ccc([N+](=O)[O-])c3nonc23)cc1 | Homo sapiens | CHEMBL3378817 | single protein format |
| CHEMBL3360531 |  |
IC50 | = | 5.0 | nM | 293.35 | O=[N+]([O-])c1ccc(SCC2CCCCC2)c2nonc12 | Homo sapiens | CHEMBL3378817 | single protein format |
| CHEMBL3360529 |  |
IC50 | = | 5.0 | nM | 398.4 | COC(=O)C(CSc1ccc([N+](=O)[O-])c2nonc12)NC(=O)OC(C)(C)C | Homo sapiens | CHEMBL3378817 | single protein format |
| CHEMBL3360535 |  |
IC50 | = | 6.0 | nM | 325.39 | O=[N+]([O-])c1ccc(SCCCCCCCCO)c2nonc12 | Homo sapiens | CHEMBL3378817 | single protein format |
| CHEMBL3352898 |  |
IC50 | = | 6.0 | nM | 331.31 | O=C(O)c1ccc(CSc2ccc([N+](=O)[O-])c3nonc23)cc1 | Homo sapiens | CHEMBL3378817 | single protein format |
| CHEMBL3360521 |  |
IC50 | = | 7.0 | nM | 359.36 | CCOC(=O)c1ccc(CSc2ccc([N+](=O)[O-])c3nonc23)cc1 | Homo sapiens | CHEMBL3378817 | single protein format |
| CHEMBL3360530 |  |
IC50 | = | 8.0 | nM | 432.41 | COC(=O)C(CSc1ccc([N+](=O)[O-])c2nonc12)NC(=O)OCc1ccccc1 | Homo sapiens | CHEMBL3378817 | single protein format |
| CHEMBL1234570 |  |
IC50 | = | 10.0 | nM | 297.34 | O=[N+]([O-])c1ccc(SCCCCCCO)c2nonc12 | Homo sapiens | CHEMBL3378817 | single protein format |
| CHEMBL3360518 |  |
IC50 | = | 10.0 | nM | 331.31 | O=C(O)Cc1ccc(Sc2ccc([N+](=O)[O-])c3nonc23)cc1 | Homo sapiens | CHEMBL3378817 | single protein format |
| CHEMBL5275770 |  |
IC50 | < | 10.0 | nM | 299.35 | O=[N+]([O-])C1=CCC(SCCCCCCO)c2nonc21 | Homo sapiens | CHEMBL5236820 | assay format |
| CHEMBL3360505 |  |
IC50 | = | 10.0 | nM | 315.35 | O=[N+]([O-])c1ccc(SCCCc2ccccc2)c2nonc12 | Homo sapiens | CHEMBL3378817 | single protein format |
| CHEMBL3360515 |  |
IC50 | = | 20.0 | nM | 422.42 | O=C(NOCc1ccccc1)c1ccc(Sc2ccc([N+](=O)[O-])c3nonc23)cc1 | Homo sapiens | CHEMBL3378817 | single protein format |
| CHEMBL2430532 |  |
IC50 | = | 20.0 | nM | 287.3 | O=[N+]([O-])c1ccc(SCc2ccccc2)c2nonc12 | Homo sapiens | CHEMBL3378817 | single protein format |
| CHEMBL3360519 |  |
IC50 | = | 20.0 | nM | 345.34 | O=C(O)CCc1ccc(Sc2ccc([N+](=O)[O-])c3nonc23)cc1 | Homo sapiens | CHEMBL3378817 | single protein format |
| CHEMBL3360520 |  |
IC50 | = | 20.0 | nM | 450.48 | O=C(CCc1ccc(Sc2ccc([N+](=O)[O-])c3nonc23)cc1)NOCc1ccccc1 | Homo sapiens | CHEMBL3378817 | single protein format |
| CHEMBL3360504 |  |
IC50 | = | 20.0 | nM | 301.33 | O=[N+]([O-])c1ccc(SCCc2ccccc2)c2nonc12 | Homo sapiens | CHEMBL3378817 | single protein format |
| CHEMBL3360528 |  |
IC50 | = | 30.0 | nM | 350.36 | O=C1CCN(C(=O)CCSc2ccc([N+](=O)[O-])c3nonc23)CC1 | Homo sapiens | CHEMBL3378817 | single protein format |
| CHEMBL3360534 |  |
IC50 | = | 30.0 | nM | 269.28 | O=[N+]([O-])c1ccc(SCCCCO)c2nonc12 | Homo sapiens | CHEMBL3378817 | single protein format |
| CHEMBL3360523 |  |
IC50 | = | 30.0 | nM | 374.38 | CONC(=O)c1ccc(CCSc2ccc([N+](=O)[O-])c3nonc23)cc1 | Homo sapiens | CHEMBL3378817 | single protein format |
| CHEMBL3360524 |  |
IC50 | = | 30.0 | nM | 283.27 | COC(=O)CCSc1ccc([N+](=O)[O-])c2nonc12 | Homo sapiens | CHEMBL3378817 | single protein format |