P27708 | PYR1_HUMAN | CAD protein (CAD)
Pfam Domain Table
Accession | Domain | Range | Color |
---|---|---|---|
PF00117 | GATase - Glutamine amidotransferase class-I | 180~355 | |
PF00185 | OTCace - Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain | 2072~2220 | |
PF00988 | CPSase_sm_chain - Carbamoyl-phosphate synthase small chain, CPSase domain | 4~137 | |
PF01979 | Amidohydro_1 - Amidohydrolase family | 1464~1522 | |
PF02142 | MGS - MGS-like domain | 1327~1427 | |
PF02729 | OTCace_N - Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain | 1924~2065 | |
PF02786 | CPSase_L_D2 - Carbamoyl-phosphate synthase L chain, ATP binding domain | 514~717 | |
PF02786 | CPSase_L_D2 - Carbamoyl-phosphate synthase L chain, ATP binding domain | 1050~1247 | |
PF02787 | CPSase_L_D3 - Carbamoyl-phosphate synthetase large chain, oligomerisation domain | 801~877 | |
PF25596 | CPSase_L_D1 - Carbamoyl phosphate synthase preATP-grasp domain | 394~510 | |
PF25596 | CPSase_L_D1 - Carbamoyl phosphate synthase preATP-grasp domain | 933~1043 |
3D structures mapped by conservation among orthologs
[ Domain: "Composite domain of metallo-dependent hydrolases" // D-HYD_C ]
[ Domain: "TIM barrels" // DHOase ]
[ Domain: "Aspartate/ornithine carbamoyltransferase" // OTCace ]
[ Domain: "Aspartate/ornithine carbamoyltransferase" // OTCace_N ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
---|---|---|---|---|---|---|---|---|---|---|
CHEMBL170214 | Ki | = | 140.0 | nM | 188.21 | O=C1N=C(CS)CC(C(=O)O)N1 | Homo sapiens | CHEMBL663682 | single protein format | |
CHEMBL29908 | Ki | = | 140.0 | nM | 190.22 | O=C1N[C@@H](CS)C[C@@H](C(=O)O)N1 | Homo sapiens | CHEMBL876720 | assay format |