P26640 | SYVC_HUMAN | Valine--tRNA ligase (VARS1)

Helixβ‑strandTurn secondary structure

Pfam Domain Table

AccessionDomainRangeColor
PF00043GST_C109–198
PF00133tRNA-synt_1309–939
PF08264Anticodon_1984–1132

 3D structures mapped by conservation among orthologs


 [ Alpha Fold Model ] (go)



 Known binders annotated in ChEMBL

 IC50 CSV
Only the first 20 rows are shown.
molecule_chembl_idstructureassay_typerelation valueunitmol_wtsmilesorganism assay_chembl_idbao_label
CHEMBL74755 IC50 = 30.0 nM 475.52 CC(C)[C@H](N)C(=O)NS(=O)(=O)CC(=O)N[C@]1(C(=O)O)[C@@H]2CN(C)C=C(C(N)=O)[C@@H]2C[C@@H]1O Homo sapiens CHEMBL816240 single protein format
CHEMBL74395 IC50 = 126.0 nM 489.55 CC[C@H](C)[C@H](N)C(=O)NS(=O)(=O)CC(=O)N[C@]1(C(=O)O)[C@@H]2CN(C)C=C(C(N)=O)[C@@H]2C[C@@H]1O Homo sapiens CHEMBL816240 single protein format
CHEMBL421500 IC50 = 290.0 nM 489.55 CC(C)C[C@H](N)C(=O)NS(=O)(=O)CC(=O)N[C@]1(C(=O)O)[C@@H]2CN(C)C=C(C(N)=O)[C@@H]2C[C@@H]1O Homo sapiens CHEMBL816240 single protein format