P25090 | FPR2_HUMAN | N-formyl peptide receptor 2 (FPR2)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00001 | 7tm_1 - 7 transmembrane receptor (rhodopsin family) | 43~302 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4536276 |  |
IC50 | = | 1.0 | nM | 382.5 | CCCCC[C@@H](O)c1c(/C=C/[C@@H](O)[C@@H](O)CCCC(=O)OC)nc(C)n1C | Homo sapiens | CHEMBL4383709 | cell-based format |
| CHEMBL4440913 |  |
IC50 | = | 25.3 | nM | 382.5 | CCCCC[C@H](O)c1c(/C=C/[C@@H](O)[C@@H](O)CCCC(=O)OC)nc(C)n1C | Homo sapiens | CHEMBL4383709 | cell-based format |
| CHEMBL4574711 |  |
IC50 | = | 26.2 | nM | 506.64 | CCCCC[C@@H](O)c1nc(-c2ccccc2)n(-c2ccccc2)c1/C=C/[C@@H](O)[C@@H](O)CCCC(=O)OC | Homo sapiens | CHEMBL4383709 | cell-based format |
| CHEMBL392438 |  |
IC50 | = | 26.3 | nM | 352.47 | CCCCC[C@H](O)/C=C/C=C\C=C\C=C\[C@@H](O)[C@@H](O)CCCC(=O)O | Homo sapiens | CHEMBL4383709 | cell-based format |
| CHEMBL4534051 |  |
IC50 | = | 27.8 | nM | 326.39 | COC(=O)CCC[C@H](O)[C@H](O)/C=C/c1nc(C)n(C)c1[C@@H](C)O | Homo sapiens | CHEMBL4383709 | cell-based format |
| CHEMBL4460558 |  |
IC50 | = | 27.8 | nM | 326.39 | COC(=O)CCC[C@H](O)[C@H](O)/C=C/c1nc(C)n(C)c1[C@H](C)O | Homo sapiens | CHEMBL4383709 | cell-based format |
| CHEMBL4436717 |  |
IC50 | = | 31.5 | nM | 354.45 | CCC[C@H](O)c1c(/C=C/[C@@H](O)[C@@H](O)CCCC(=O)OC)nc(C)n1C | Homo sapiens | CHEMBL4383709 | cell-based format |
| CHEMBL4462922 |  |
IC50 | = | 32.4 | nM | 506.64 | CCCCC[C@H](O)c1nc(-c2ccccc2)n(-c2ccccc2)c1/C=C/[C@@H](O)[C@@H](O)CCCC(=O)OC | Homo sapiens | CHEMBL4383709 | cell-based format |
| CHEMBL4582724 |  |
IC50 | = | 37.3 | nM | 459.58 | CCCCC[C@@H](O)c1nc(-c2ccccc2)oc1/C=C/[C@@H](O)[C@@H](O)CCCC(=O)OC(C)C | Homo sapiens | CHEMBL4383709 | cell-based format |
| CHEMBL4551559 |  |
IC50 | = | 40.3 | nM | 354.45 | CCC[C@@H](O)c1c(/C=C/[C@@H](O)[C@@H](O)CCCC(=O)OC)nc(C)n1C | Homo sapiens | CHEMBL4383709 | cell-based format |
| CHEMBL4784510 |  |
IC50 | = | 57.0 | nM | 361.35 | COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccccc2)c(F)c1 | Homo sapiens | CHEMBL4725985 | cell-based format |
| CHEMBL4434857 |  |
IC50 | = | 69.6 | nM | 459.58 | CCCCC[C@H](O)c1nc(-c2ccccc2)oc1/C=C/[C@@H](O)[C@@H](O)CCCC(=O)OC(C)C | Homo sapiens | CHEMBL4383709 | cell-based format |