P24928 | RPB1_HUMAN | DNA-directed RNA polymerase II subunit RPB1 (POLR2A)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00623 | RNA_pol_Rpb1_2 | 356–521 | |
| PF04983 | RNA_pol_Rpb1_3 | 525–691 | |
| PF04990 | RNA_pol_Rpb1_7 | 1164–1299 | |
| PF04992 | RNA_pol_Rpb1_6 | 896–1079 | |
| PF04997 | RNA_pol_Rpb1_1 | 16–354 | |
| PF04998 | RNA_pol_Rpb1_5 | 830–895 | |
| PF04998 | RNA_pol_Rpb1_5 | 1080–1163 | |
| PF04998 | RNA_pol_Rpb1_5 | 1300–1425 | |
| PF05000 | RNA_pol_Rpb1_4 | 718–823 | |
| PF05001 | RNA_pol_Rpb1_R | 1589–1600 | |
| PF05001 | RNA_pol_Rpb1_R | 1616–1629 | |
| PF05001 | RNA_pol_Rpb1_R | 1630–1643 | |
| PF05001 | RNA_pol_Rpb1_R | 1644–1657 | |
| PF05001 | RNA_pol_Rpb1_R | 1658–1671 | |
| PF05001 | RNA_pol_Rpb1_R | 1672–1685 | |
| PF05001 | RNA_pol_Rpb1_R | 1686–1699 | |
| PF05001 | RNA_pol_Rpb1_R | 1700–1713 | |
| PF05001 | RNA_pol_Rpb1_R | 1714–1727 | |
| PF05001 | RNA_pol_Rpb1_R | 1728–1741 | |
| PF05001 | RNA_pol_Rpb1_R | 1742–1755 | |
| PF05001 | RNA_pol_Rpb1_R | 1749–1762 | |
| PF05001 | RNA_pol_Rpb1_R | 1757–1769 | |
| PF05001 | RNA_pol_Rpb1_R | 1763–1776 | |
| PF05001 | RNA_pol_Rpb1_R | 1770–1783 | |
| PF05001 | RNA_pol_Rpb1_R | 1778–1790 | |
| PF05001 | RNA_pol_Rpb1_R | 1784–1797 | |
| PF05001 | RNA_pol_Rpb1_R | 1791–1804 | |
| PF05001 | RNA_pol_Rpb1_R | 1798–1811 | |
| PF05001 | RNA_pol_Rpb1_R | 1805–1818 | |
| PF05001 | RNA_pol_Rpb1_R | 1826–1839 | |
| PF05001 | RNA_pol_Rpb1_R | 1833–1846 | |
| PF05001 | RNA_pol_Rpb1_R | 1841–1853 | |
| PF05001 | RNA_pol_Rpb1_R | 1847–1860 | |
| PF05001 | RNA_pol_Rpb1_R | 1855–1867 | |
| PF05001 | RNA_pol_Rpb1_R | 1861–1874 | |
| PF05001 | RNA_pol_Rpb1_R | 1868–1881 | |
| PF05001 | RNA_pol_Rpb1_R | 1875–1888 | |
| PF05001 | RNA_pol_Rpb1_R | 1882–1895 | |
| PF05001 | RNA_pol_Rpb1_R | 1889–1902 | |
| PF05001 | RNA_pol_Rpb1_R | 1896–1909 | |
| PF05001 | RNA_pol_Rpb1_R | 1904–1916 | |
| PF05001 | RNA_pol_Rpb1_R | 1910–1923 | |
| PF05001 | RNA_pol_Rpb1_R | 1917–1930 | |
| PF05001 | RNA_pol_Rpb1_R | 1924–1936 | |
| PF05001 | RNA_pol_Rpb1_R | 1931–1947 | |
| PF05001 | RNA_pol_Rpb1_R | 1941–1954 | |
| PF05001 | RNA_pol_Rpb1_R | 1948–1960 |
3D structures mapped by conservation among orthologs
[ Domain: "double psi" // RNA_pol_Rpb1_2 ]
[ Domain: "MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase" // RNA_pol_Rpb1_2_1 ]
[ Domain: "permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit" // RNA_pol_Rpb1_7 ]
[ Domain: "ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit" // RNAP_II_Rpb1_C ]
[ Domain: "N-terminal domain in RNA-polymerase beta-prime subunit" // RNA_pol_Rpb1_1 ]
[ Domain: "central helical domain in RNA-polymerase beta-prime subunit" // RNA_pol_Rpb1_5_3rd ]
[ Domain: "third helical domain in yeast RNA-polymerase II beta-prime subunit" // RNA_pol_Rpb1_6 ]
[ Domain: "second helical domain in RNA-polymerase beta-prime subunit" // RNA_pol_Rpb1_4 ]
[ Domain: "first helical domain in RNA-polymerase beta-prime subunit" // RNA_pol_Rpb1_3 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|