P23786 | CPT2_HUMAN | Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00755 | Carn_acyltransf - Choline/Carnitine o-acyltransferase | 52~642 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL1231507 |  |
IC50 | = | 140.0 | nM | 398.63 | CCCCCCCCCCCCCCCC(=O)N[C@H](CC(=O)[O-])C[N+](C)(C)C | Homo sapiens | CHEMBL2217026 | single protein format |
| CHEMBL1231506 |  |
IC50 | = | 160.0 | nM | 399.62 | CCCCCCCCCCCCCCNC(=O)N[C@H](CC(=O)[O-])C[N+](C)(C)C | Homo sapiens | CHEMBL2217026 | single protein format |
| CHEMBL3431801 |  |
IC50 | = | 193.4 | nM | 464.56 | O=C([C@H]1CCCCN1C(=O)COc1ccccc1)N1Cc2ccc(OC3CCOCC3)cc2C1 | Homo sapiens | CHEMBL3431931 | single protein format |
| CHEMBL3431602 |  |
IC50 | = | 285.7 | nM | 518.95 | COc1ccc(Cl)cc1S(=O)(=O)N1CCc2c(C)cc(C(=O)Nc3ccc(C(=O)O)c(F)c3)cc21 | Homo sapiens | CHEMBL3431931 | single protein format |
| CHEMBL3431916 |  |
IC50 | = | 311.6 | nM | 502.93 | COc1ccc(Cl)cc1S(=O)(=O)N1COc2c(C)cc(C(=O)Nc3ccc(C(=O)O)cc3)cc21 | Homo sapiens | CHEMBL3431931 | single protein format |
| CHEMBL3431605 |  |
IC50 | = | 325.7 | nM | 500.96 | COc1ccc(Cl)cc1S(=O)(=O)N1CCc2c(C)cc(C(=O)Nc3ccc(C(=O)O)cc3)cc21 | Homo sapiens | CHEMBL3431931 | single protein format |
| CHEMBL3431735 |  |
IC50 | = | 387.6 | nM | 484.0 | O=C([C@H]1CCCCN1C(=O)COc1ccccc1)N1Cc2cc(Cl)c(N3CCOCC3)cc2C1 | Homo sapiens | CHEMBL3431931 | single protein format |
| CHEMBL3431499 |  |
IC50 | = | 452.8 | nM | 500.96 | COc1ccc(Cl)cc1S(=O)(=O)N1C[C@@H](C)c2ccc(C(=O)Nc3ccc(C(=O)O)cc3)cc21 | Homo sapiens | CHEMBL3431931 | single protein format |
| CHEMBL3431736 |  |
IC50 | = | 468.2 | nM | 408.5 | CCOc1ccc2c(c1)CN(C(=O)[C@H]1CCCCN1C(=O)COc1ccccc1)C2 | Homo sapiens | CHEMBL3431931 | single protein format |
| CHEMBL3431739 |  |
IC50 | = | 472.5 | nM | 434.54 | O=C([C@H]1CCCCN1C(=O)COc1ccccc1)N1Cc2ccc(C3CCOC3)cc2C1 | Homo sapiens | CHEMBL3431931 | single protein format |
| CHEMBL3431802 |  |
IC50 | = | 489.2 | nM | 450.54 | O=C([C@H]1CCCCN1C(=O)COc1ccccc1)N1Cc2ccc(O[C@@H]3CCOC3)cc2C1 | Homo sapiens | CHEMBL3431931 | single protein format |
| CHEMBL3431799 |  |
IC50 | = | 507.2 | nM | 482.55 | O=C([C@H]1CCCCN1C(=O)COc1ccccc1)N1Cc2cc(F)c(OC3CCOCC3)cc2C1 | Homo sapiens | CHEMBL3431931 | single protein format |
| CHEMBL3431478 |  |
IC50 | = | 536.6 | nM | 512.97 | CCn1cc(S(=O)(=O)c2cc(Cl)ccc2OC)c2cc(C(=O)Nc3ccc(C(=O)O)cc3)ccc21 | Homo sapiens | CHEMBL3431931 | single protein format |
| CHEMBL3431800 |  |
IC50 | = | 540.3 | nM | 467.54 | O=C([C@H]1CCCCN1C(=O)COc1ccccc1)N1Cc2cc(F)c(N3CCOCC3)cc2C1 | Homo sapiens | CHEMBL3431931 | single protein format |
| CHEMBL3431777 |  |
IC50 | = | 544.5 | nM | 441.96 | O=C([C@H]1CCCCN1C(=O)COc1ccccc1)N1CCN(c2cccc(Cl)c2)CC1 | Homo sapiens | CHEMBL3431931 | single protein format |
| CHEMBL3431803 |  |
IC50 | = | 550.5 | nM | 450.54 | O=C([C@H]1CCCCN1C(=O)COc1ccccc1)N1Cc2ccc(O[C@H]3CCOC3)cc2C1 | Homo sapiens | CHEMBL3431931 | single protein format |
| CHEMBL3431915 |  |
IC50 | = | 553.9 | nM | 516.96 | COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2c(C)cc(C(=O)Nc3ccc(C(=O)O)cc3)cc21 | Homo sapiens | CHEMBL3431931 | single protein format |
| CHEMBL3431914 |  |
IC50 | = | 578.2 | nM | 537.38 | COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2c(Cl)cc(C(=O)Nc3ccc(C(=O)O)cc3)cc21 | Homo sapiens | CHEMBL3431931 | single protein format |
| CHEMBL3431909 |  |
IC50 | = | 579.4 | nM | 498.94 | COc1ccc(Cl)cc1S(=O)(=O)c1cn(C)c2ccc(C(=O)Nc3ccc(C(=O)O)cc3)cc12 | Homo sapiens | CHEMBL3431931 | single protein format |
| CHEMBL3431898 |  |
IC50 | = | 583.5 | nM | 518.95 | COc1ccc(Cl)cc1S(=O)(=O)N1CC(C)c2ccc(C(=O)Nc3ccc(C(=O)O)c(F)c3)cc21 | Homo sapiens | CHEMBL3431931 | single protein format |