P23471 | PTPRZ_HUMAN | Receptor-type tyrosine-protein phosphatase zeta (PTPRZ1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00041 | fn3 - Fibronectin type III domain | 313~405 | |
| PF00102 | Y_phosphatase - Protein-tyrosine phosphatase | 1750~1991 | |
| PF00102 | Y_phosphatase - Protein-tyrosine phosphatase | 2048~2280 | |
| PF00194 | Carb_anhydrase - Eukaryotic-type carbonic anhydrase | 45~299 |
3D structures mapped by conservation among orthologs
[ Domain: "Carbonic anhydrase" // Carb_anhydrase ]
[ Domain: "(Phosphotyrosine protein) phosphatases II" // Y_phosphatase ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4285054 |  |
IC50 | = | 100.0 | nM | 384.37 | FC(F)(F)Sc1ccc(COc2ccc(SC(F)(F)F)cc2)cc1 | Homo sapiens | CHEMBL4253962 | single protein format |
| CHEMBL4278170 |  |
IC50 | = | 100.0 | nM | 397.41 | FC(F)(F)Sc1ccc(CNCc2ccc(SC(F)(F)F)cc2)cc1 | Homo sapiens | CHEMBL4253962 | single protein format |
| CHEMBL4286807 |  |
IC50 | = | 800.0 | nM | 425.42 | O=C(Cc1ccc(SC(F)(F)F)cc1)NCc1ccc(SC(F)(F)F)cc1 | Homo sapiens | CHEMBL4253962 | single protein format |