P23025 | XPA_HUMAN | DNA repair protein complementing XP-A cells (XPA)

Pfam Domain Table

AccessionDomainRangeColor
PF01286XPA_N - XPA protein N-terminal104~133
PF05181XPA_C - XPA protein C-terminus135~186

3D structures mapped by conservation among orthologs

[ Domain: "Putative DNA-binding domain" // XPA_C ]

 PyMOL session

[ Domain: "LIM domain-like" // XPA_N ]

 PyMOL session


[ Alpha Fold Model ] (go)



Known binders annotated in ChEMBL

 IC50 CSV
Only the first 20 rows are shown.
molecule_chembl_idstructureassay_typerelation valueunitmol_wtsmilesorganism assay_chembl_idbao_label
CHEMBL4065804 IC50 = 820.0 nM 575.4 CC1=NN(c2ccc(Cl)c(C(=O)O)c2)C(=O)/C1=C\c1ccc(-c2ccc(Cl)c(C(=O)OCc3ccccc3)c2)o1 Homo sapiens CHEMBL4020074 cell-based format