P22888 | LSHR_HUMAN | Lutropin-choriogonadotropic hormone receptor (LHCGR)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00001 | 7tm_1 - 7 transmembrane receptor (rhodopsin family) | 376~623 | |
| PF13306 | LRR_5 - BspA type Leucine rich repeat region (6 copies) | 61~133 | |
| PF13306 | LRR_5 - BspA type Leucine rich repeat region (6 copies) | 160~240 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4537998 |  |
IC50 | = | 97.0 | nM | 473.94 | O=C(Nc1ccc(Oc2ccc(F)cc2)cc1)N1CCc2ncccc2[C@@H]1c1ccc(Cl)cc1 | Homo sapiens | CHEMBL4323883 | cell-based format |
| CHEMBL4458424 |  |
IC50 | = | 185.0 | nM | 459.46 | O=C(Nc1cnc(Oc2ccc(F)cc2)nc1)N1CCc2ncccc2[C@@H]1c1ccc(F)cc1 | Homo sapiens | CHEMBL4884139 | single protein format |
| CHEMBL246321 |  |
Ki | = | 0.311 | nM | 539.68 | CC(C)(C)c1ccc(-n2nc(-c3cccnc3)cc2CCCCC(=O)N[C@@H](Cc2ccc(O)cc2)C(N)=O)cc1 | Homo sapiens | CHEMBL886764 | single protein format |