P22736 | NR4A1_HUMAN | Nuclear receptor subfamily 4 group A member 1 (NR4A1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00104 | Hormone_recep - Ligand-binding domain of nuclear hormone receptor | 402~578 | |
| PF00105 | zf-C4 - Double treble clef zinc finger, C4 type | 266~334 |
3D structures mapped by conservation among orthologs
[ Domain: "Nuclear receptor ligand-binding domain" // Hormone_recep_1 ]
[ Domain: "Nuclear receptor ligand-binding domain" // Hormone_recep ]
[ Domain: "LIM domain-like" // zf-C4 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL259355 |  |
IC50 | < | 195.0 | nM | 243.31 | Cc1ccc(C)n1C(Cc1ccccc1)C(=O)O | Homo sapiens | CHEMBL1613981 | single protein format |
| CHEMBL1381627 |  |
IC50 | = | 492.62 | nM | 458.45 | COc1cc(-c2nnc(SCc3cc(=O)oc4cc(O)c(O)cc34)o2)cc(OC)c1OC | Homo sapiens | CHEMBL1613981 | single protein format |
| CHEMBL1575787 |  |
IC50 | = | 558.14 | nM | 418.34 | CCOc1ccc(C(=O)Nc2ccc(N3CCN(C)CC3)cc2)cc1Br | Homo sapiens | CHEMBL1613981 | single protein format |
| CHEMBL1566165 |  |
IC50 | = | 725.2 | nM | 402.45 | O=C(Nc1ccc2nc(-c3ccco3)c(-c3ccco3)nc2c1)N1CCCCCC1 | Homo sapiens | CHEMBL1613981 | single protein format |
| CHEMBL1504655 |  |
IC50 | = | 783.41 | nM | 221.28 | Cc1ccc(C)n1-c1sccc1C(=O)O | Homo sapiens | CHEMBL1613981 | single protein format |
| CHEMBL1432963 |  |
IC50 | = | 963.49 | nM | 212.72 | Cc1cc(N)ccc1N1CCCC1.Cl | Homo sapiens | CHEMBL1613981 | single protein format |