P22735 | TGM1_HUMAN | Protein-glutamine gamma-glutamyltransferase K (TGM1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00868 | Transglut_N - Transglutaminase family | 122~226 | |
| PF00927 | Transglut_C - Transglutaminase family, C-terminal ig like domain | 579~683 | |
| PF00927 | Transglut_C - Transglutaminase family, C-terminal ig like domain | 691~787 | |
| PF01841 | Transglut_core - Transglutaminase-like superfamily | 374~460 |
3D structures mapped by conservation among orthologs
[ Domain: "Immunoglobulin/Fibronectin type III/E set domains/PapD-like" // Transglut_C ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL2086889 |  |
IC50 | = | 18.0 | nM | 313.32 | CCn1nc(-c2ccc(OC)cc2)nc2c(=O)n(C)c(=O)nc1-2 | Homo sapiens | CHEMBL2091158 | single protein format |
| CHEMBL193220 |  |
IC50 | = | 250.0 | nM | 344.82 | CC(=O)CSc1n[n+]2c(C)csc2s1.[O-][Cl+3]([O-])([O-])[O-] | Homo sapiens | CHEMBL827899 | assay format |
| CHEMBL2152090 |  |
IC50 | = | 910.0 | nM | 443.53 | C=CC(=O)NC1CCN(S(=O)(=O)c2ccc(NC(=O)OCc3ccccc3)cc2)CC1 | Homo sapiens | CHEMBL2155210 | single protein format |
| CHEMBL2086891 |  |
IC50 | = | 950.0 | nM | 429.93 | C=CC(=O)Nc1ccc(S(=O)(=O)N2CCN(C(=O)OC(C)(C)C)CC2)c(Cl)c1 | Homo sapiens | CHEMBL2091158 | single protein format |