P21462 | FPR1_HUMAN | fMet-Leu-Phe receptor (FPR1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00001 | 7tm_1 - 7 transmembrane receptor (rhodopsin family) | 43~301 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL266802 |  |
IC50 | = | 2.0 | nM | 542.7 | CSCC[C@H](NC(=O)Nc1ccc(C)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)O | Homo sapiens | CHEMBL820116 | single protein format |
| CHEMBL267388 |  |
IC50 | = | 2.0 | nM | 563.12 | CSCC[C@H](NC(=O)Nc1ccc(Cl)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)O | Homo sapiens | CHEMBL820116 | single protein format |
| CHEMBL7753 |  |
IC50 | = | 2.0 | nM | 558.7 | COc1ccc(NC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(C)C)C(=O)NC(Cc2ccccc2)C(=O)O)cc1 | Homo sapiens | CHEMBL820116 | single protein format |
| CHEMBL267179 |  |
IC50 | = | 20.0 | nM | 437.56 | CSCC[C@H](NC=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)O | Homo sapiens | CHEMBL820116 | single protein format |
| CHEMBL7520 |  |
IC50 | = | 30.0 | nM | 528.68 | CSCC[C@H](NC(=O)Nc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)O | Homo sapiens | CHEMBL820116 | single protein format |
| CHEMBL6997 |  |
IC50 | = | 100.0 | nM | 542.7 | CSCC[C@H](NC(=O)Nc1cccc(C)c1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)O | Homo sapiens | CHEMBL820116 | single protein format |
| CHEMBL265408 |  |
IC50 | = | 300.0 | nM | 508.69 | CCCCNC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)O | Homo sapiens | CHEMBL820116 | single protein format |
| CHEMBL266089 |  |
IC50 | = | 300.0 | nM | 492.64 | C=C(C)NC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)O | Homo sapiens | CHEMBL820116 | single protein format |
| CHEMBL7226 |  |
IC50 | = | 800.0 | nM | 542.7 | CSCC[C@H](NC(=O)NCc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)O | Homo sapiens | CHEMBL820116 | single protein format |
| CHEMBL6779 |  |
IC50 | = | 900.0 | nM | 586.8 | CSCC[C@H](NC(=O)NC12CC3CC(CC(C3)C1)C2)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)O | Homo sapiens | CHEMBL820116 | single protein format |
| CHEMBL268823 |  |
IC50 | = | 1000.0 | nM | 508.69 | CSCC[C@H](NC(=O)NCC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)O | Homo sapiens | CHEMBL820116 | single protein format |
| CHEMBL7214 |  |
IC50 | = | 1000.0 | nM | 480.63 | CCNC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)O | Homo sapiens | CHEMBL820116 | single protein format |
| CHEMBL267179 | |
Ki | = | 42.0 | nM | 437.56 | CSCC[C@H](NC=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)O | Homo sapiens | CHEMBL887899 | single protein format |