P20815 | CP3A5_HUMAN | Cytochrome P450 3A5 (CYP3A5)
Pfam Domain Table
Accession | Domain | Range | Color |
---|---|---|---|
PF00067 | p450 - Cytochrome P450 | 39~492 |
3D structures mapped by conservation among orthologs
[ Domain: "Cytochrome P450" // p450 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
---|---|---|---|---|---|---|---|---|---|---|
CHEMBL1159650 | IC50 | = | 44.0 | nM | 466.98 | CCC(=O)O[C@]1(C(=O)CCl)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C | Homo sapiens | CHEMBL4325677 | cell-based format | |
CHEMBL157101 | IC50 | = | 120.0 | nM | 531.44 | CC(=O)N1CCN(c2ccc(OCC3COC(Cn4ccnc4)(c4ccc(Cl)cc4Cl)O3)cc2)CC1 | Homo sapiens | CHEMBL3887124 | single protein format | |
CHEMBL75 | IC50 | = | 513.0 | nM | 531.44 | CC(=O)N1CCN(c2ccc(OC[C@H]3CO[C@](Cn4ccnc4)(c4ccc(Cl)cc4Cl)O3)cc2)CC1 | Homo sapiens | CHEMBL4325677 | cell-based format |