P20749 | BCL3_HUMAN | B-cell lymphoma 3 protein (BCL3)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00023 | Ank - Ankyrin repeat | 134~155 | |
| PF12796 | Ank_2 - Ankyrin repeats (3 copies) | 186~272 | |
| PF12796 | Ank_2 - Ankyrin repeats (3 copies) | 280~356 |
3D structures mapped by conservation among orthologs
[ Domain: "Ankyrin repeat" // Ank_2 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4562558 |  |
IC50 | = | 11.95 | nM | 401.44 | COc1cccc(C(=O)NCCN2CCOCC2)c1NC(=O)c1ccccc1F | Homo sapiens | CHEMBL4422027 | cell-based format |
| CHEMBL4558803 |  |
IC50 | = | 45.43 | nM | 371.41 | O=C(Nc1ccccc1C(=O)NCCN1CCOCC1)c1ccccc1F | Homo sapiens | CHEMBL4422029 | cell-based format |
| CHEMBL1383390 |  |
IC50 | = | 61.7 | nM | 383.45 | COc1ccc(C(=O)Nc2ccccc2C(=O)NCCN2CCOCC2)cc1 | Homo sapiens | CHEMBL4422027 | cell-based format |
| CHEMBL4534875 |  |
IC50 | = | 237.8 | nM | 389.4 | O=C(Nc1ccccc1C(=O)NCCN1CCOCC1)c1cc(F)cc(F)c1 | Homo sapiens | CHEMBL4422029 | cell-based format |
| CHEMBL4522736 |  |
IC50 | = | 705.9 | nM | 389.4 | O=C(NCCN1CCOCC1)c1ccccc1NC(=O)c1c(F)cccc1F | Homo sapiens | CHEMBL4422029 | cell-based format |
| CHEMBL4451393 |  |
IC50 | = | 988.87 | nM | 389.4 | O=C(Nc1ccccc1C(=O)NCCN1CCOCC1)c1ccc(F)cc1F | Homo sapiens | CHEMBL4422029 | cell-based format |