P19320 | VCAM1_HUMAN | Vascular cell adhesion protein 1 (VCAM1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00047 | ig - Immunoglobulin domain | 232~302 | |
| PF05790 | C2-set - Immunoglobulin C2-set domain | 133~221 | |
| PF05790 | C2-set - Immunoglobulin C2-set domain | 421~508 | |
| PF07679 | I-set - Immunoglobulin I-set domain | 27~112 | |
| PF07679 | I-set - Immunoglobulin I-set domain | 321~399 | |
| PF13927 | Ig_3 - Immunoglobulin domain | 517~583 | |
| PF13927 | Ig_3 - Immunoglobulin domain | 605~672 |
3D structures mapped by conservation among orthologs
[ Domain: "Immunoglobulin/Fibronectin type III/E set domains/PapD-like" // C2-set ]
[ Domain: "Immunoglobulin/Fibronectin type III/E set domains/PapD-like" // I-set_5 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL119039 |  |
IC50 | = | 5.0 | nM | 350.4 | CNC(=O)c1cc2c(Oc3ccc(-n4cccn4)cc3)cncc2s1 | Homo sapiens | CHEMBL818854 | cell-based format |
| CHEMBL117894 |  |
IC50 | = | 6.0 | nM | 366.47 | CNC(=O)c1cc2c(Oc3ccc(-c4cccs4)cc3)cncc2s1 | Homo sapiens | CHEMBL818854 | cell-based format |
| CHEMBL326120 |  |
IC50 | = | 17.0 | nM | 336.38 | NC(=O)c1cc2c(Oc3ccc(-n4ccnc4)cc3)cncc2s1 | Homo sapiens | CHEMBL818854 | cell-based format |
| CHEMBL325184 |  |
IC50 | = | 19.0 | nM | 350.4 | CNC(=O)c1cc2c(Oc3ccc(-n4ccnc4)cc3)cncc2s1 | Homo sapiens | CHEMBL818854 | cell-based format |
| CHEMBL119183 |  |
IC50 | = | 23.0 | nM | 314.37 | COCc1ccc(Oc2cncc3sc(C(N)=O)cc23)cc1 | Homo sapiens | CHEMBL818854 | cell-based format |
| CHEMBL116070 |  |
IC50 | = | 48.0 | nM | 349.21 | NC(=O)c1cc2c(Oc3ccc(Br)cc3)cncc2s1 | Homo sapiens | CHEMBL818854 | cell-based format |
| CHEMBL117936 |  |
IC50 | = | 64.0 | nM | 285.33 | NC(=O)c1cc2c(Oc3ccc(N)cc3)cncc2s1 | Homo sapiens | CHEMBL818854 | cell-based format |
| CHEMBL118074 |  |
IC50 | = | 70.0 | nM | 318.79 | CNC(=O)c1cc2c(Oc3ccc(Cl)cc3)cncc2s1 | Homo sapiens | CHEMBL818856 | cell-based format |
| CHEMBL118089 |  |
IC50 | = | 74.0 | nM | 354.43 | CNC(=O)c1cc2c(Oc3ccc(C4(CO)CC4)cc3)cncc2s1 | Homo sapiens | CHEMBL818854 | cell-based format |
| CHEMBL115637 |  |
IC50 | = | 79.0 | nM | 360.44 | CNC(=O)c1cc2c(Oc3ccc(-c4ccccc4)cc3)cncc2s1 | Homo sapiens | CHEMBL818854 | cell-based format |
| CHEMBL117198 |  |
IC50 | = | 85.0 | nM | 295.32 | N#Cc1ccc(Oc2cncc3sc(C(N)=O)cc23)cc1 | Homo sapiens | CHEMBL818854 | cell-based format |
| CHEMBL115971 |  |
IC50 | = | 91.0 | nM | 309.35 | CNC(=O)c1cc2c(Oc3ccc(C#N)cc3)cncc2s1 | Homo sapiens | CHEMBL818854 | cell-based format |
| CHEMBL117279 |  |
IC50 | = | 120.0 | nM | 416.5 | CNC(=O)c1cc2c(Oc3ccc(COCCOCCOC)cc3)cncc2s1 | Homo sapiens | CHEMBL818854 | cell-based format |
| CHEMBL324133 |  |
IC50 | = | 130.0 | nM | 332.81 | CN(C)C(=O)c1cc2c(Oc3ccc(Cl)cc3)cncc2s1 | Homo sapiens | CHEMBL818854 | cell-based format |
| CHEMBL119732 |  |
IC50 | = | 140.0 | nM | 298.37 | CCc1ccc(Oc2cncc3sc(C(N)=O)cc23)cc1 | Homo sapiens | CHEMBL818854 | cell-based format |
| CHEMBL115431 |  |
IC50 | = | 170.0 | nM | 480.53 | CCOCCOCCOCC(F)(F)c1ccc(Oc2cncc3sc(C(=O)NC)cc23)cc1 | Homo sapiens | CHEMBL818854 | cell-based format |
| CHEMBL6248 |  |
IC50 | = | 175.0 | nM | 265.33 | COc1ccc2sc(C(N)=O)c(OC(C)C)c2c1 | Homo sapiens | CHEMBL815900 | cell-based format |
| CHEMBL118022 |  |
IC50 | = | 191.0 | nM | 300.34 | NC(=O)c1cc2c(Oc3ccc(CO)cc3)cncc2s1 | Homo sapiens | CHEMBL818854 | cell-based format |
| CHEMBL119705 |  |
IC50 | = | 240.0 | nM | 351.39 | CNC(=O)c1cc2c(Oc3ccc(-n4cncn4)cc3)cncc2s1 | Homo sapiens | CHEMBL818854 | cell-based format |
| CHEMBL119599 |  |
IC50 | = | 330.0 | nM | 383.65 | NC(=O)c1cc2c(Oc3ccc(Cl)cc3Br)cncc2s1 | Homo sapiens | CHEMBL818854 | cell-based format |