P18858 | DNLI1_HUMAN | DNA ligase 1 (LIG1)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF01068 | DNA_ligase_A_M | 542–746 | |
| PF04675 | DNA_ligase_A_N | 288–464 | |
| PF04679 | DNA_ligase_A_C | 771–882 |
3D structures mapped by conservation among orthologs
[ Domain: "Nucleic acid-binding proteins" // DNA_ligase_A_C ]
[ Domain: "ATP-dependent DNA ligase DNA-binding domain" // DNA_ligase_A_N ]
[ Domain: "ATP-grasp" // DNA_ligase_A_M ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL468590 |  |
IC50 | = | 600.0 | nM | 310.33 | Cc1oc(C(=O)O)cc1CSCc1cc(C(=O)O)c(C)o1 | Homo sapiens | CHEMBL979103 | single protein format |
| CHEMBL2348305 |  |
IC50 | = | 1000.0 | nM | 511.1 | N[C@H](CO)Cc1cc(I)c(Oc2ccc(O)cc2)c(I)c1 | Homo sapiens | CHEMBL4337639 | single protein format |