P18669 | PGAM1_HUMAN | Phosphoglycerate mutase 1 (PGAM1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00300 | His_Phos_1 - Histidine phosphatase superfamily (branch 1) | 6~128 | |
| PF00300 | His_Phos_1 - Histidine phosphatase superfamily (branch 1) | 140~213 |
3D structures mapped by conservation among orthologs
[ Domain: "Phosphoglycerate mutase-like" // His_Phos_1 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4760337 |  |
IC50 | = | 97.0 | nM | 477.54 | O=C1c2ccccc2C(=O)c2c1cc(NS(=O)(=O)c1ccc(C3CCCCC3)cc1)c(O)c2O | Homo sapiens | CHEMBL4666358 | single protein format |
| CHEMBL5270603 |  |
IC50 | = | 105.0 | nM | 464.5 | O=C1c2ccccc2C(=O)c2c1cc(NS(=O)(=O)c1ccc(N3CCCC3)cc1)c(O)c2O | Homo sapiens | CHEMBL5248662 | single protein format |
| CHEMBL4763924 |  |
IC50 | = | 140.0 | nM | 505.94 | O=C1c2ccccc2C(=O)c2c1cc(NS(=O)(=O)c1ccc(-c3ccc(Cl)cc3)cc1)c(O)c2O | Homo sapiens | CHEMBL4666358 | single protein format |
| CHEMBL4789955 |  |
IC50 | = | 190.0 | nM | 445.45 | O=C1c2ccccc2C(=O)c2c1cc(NS(=O)(=O)c1ccc3ccccc3c1)c(O)c2O | Homo sapiens | CHEMBL4666358 | single protein format |
| CHEMBL4741748 |  |
IC50 | = | 250.0 | nM | 471.49 | O=C1c2ccccc2C(=O)c2c1cc(NS(=O)(=O)c1ccc(-c3ccccc3)cc1)c(O)c2O | Homo sapiens | CHEMBL4666358 | single protein format |
| CHEMBL4784572 |  |
IC50 | = | 260.0 | nM | 489.48 | O=C1c2ccccc2C(=O)c2c1cc(NS(=O)(=O)c1ccc(-c3ccc(F)cc3)cc1)c(O)c2O | Homo sapiens | CHEMBL4666358 | single protein format |
| CHEMBL5287487 |  |
IC50 | = | 270.0 | nM | 429.84 | O=C1c2ccccc2C(=O)c2c1cc(NS(=O)(=O)c1ccc(Cl)cc1)c(O)c2O | Homo sapiens | CHEMBL5248662 | single protein format |
| CHEMBL4742013 |  |
IC50 | = | 330.0 | nM | 478.53 | O=C1c2ccccc2C(=O)c2c1cc(NS(=O)(=O)c1ccc(N3CCCCC3)cc1)c(O)c2O | Homo sapiens | CHEMBL4666358 | single protein format |
| CHEMBL4757633 |  |
IC50 | = | 360.0 | nM | 409.42 | Cc1ccc(S(=O)(=O)Nc2cc3c(c(O)c2O)C(=O)c2ccccc2C3=O)cc1 | Homo sapiens | CHEMBL4666358 | single protein format |
| CHEMBL4759807 |  |
IC50 | = | 480.0 | nM | 425.42 | COc1cccc(S(=O)(=O)Nc2cc3c(c(O)c2O)C(=O)c2ccccc2C3=O)c1 | Homo sapiens | CHEMBL4666358 | single protein format |
| CHEMBL5277511 |  |
IC50 | = | 490.0 | nM | 456.4 | Cc1cc([C@H]2Oc3cc(O)cc(O)c3C[C@H]2OC(=O)c2cc(O)c(O)c(O)c2)cc(O)c1O | Homo sapiens | CHEMBL5248676 | single protein format |
| CHEMBL4752163 |  |
IC50 | = | 490.0 | nM | 451.5 | CC(C)(C)c1ccc(S(=O)(=O)Nc2cc3c(c(O)c2O)C(=O)c2ccccc2C3=O)cc1 | Homo sapiens | CHEMBL4666358 | single protein format |
| CHEMBL297453 |  |
IC50 | = | 490.0 | nM | 458.38 | O=C(O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c1cc(O)c(O)c(O)c1)c1cc(O)c(O)c(O)c1 | Homo sapiens | CHEMBL4222127 | cell-based format |
| CHEMBL4228862 |  |
IC50 | = | 500.0 | nM | 481.53 | O=c1c2c(O)cccc2oc2cc(NS(=O)(=O)c3ccc(C4CCCCC4)cc3)c(O)c(O)c12 | Homo sapiens | CHEMBL4222108 | single protein format |
| CHEMBL186784 |  |
IC50 | = | 500.0 | nM | 196.21 | O=c1c2ccccc2oc2ccccc12 | Homo sapiens | CHEMBL4713836 | single protein format |
| CHEMBL4743623 |  |
IC50 | = | 550.0 | nM | 435.87 | O=C1c2ccccc2C(=O)c2c1cc(NS(=O)(=O)c1ccc(Cl)s1)c(O)c2O | Homo sapiens | CHEMBL4666358 | single protein format |
| CHEMBL4798515 |  |
IC50 | = | 550.0 | nM | 497.83 | O=C1c2ccccc2C(=O)c2c1cc(NS(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1)c(O)c2O | Homo sapiens | CHEMBL4666358 | single protein format |
| CHEMBL4762201 |  |
IC50 | = | 630.0 | nM | 481.38 | O=C1c2ccccc2C(=O)c2c1cc(NS(=O)(=O)c1ccc(F)c(C(F)(F)F)c1)c(O)c2O | Homo sapiens | CHEMBL4666358 | single protein format |
| CHEMBL5274803 |  |
IC50 | = | 770.0 | nM | 438.46 | CN(C)c1ccc(S(=O)(=O)Nc2cc3c(c(O)c2O)C(=O)c2ccccc2C3=O)cc1 | Homo sapiens | CHEMBL5248662 | single protein format |
| CHEMBL4787732 |  |
IC50 | = | 840.0 | nM | 401.42 | O=C1c2ccccc2C(=O)c2c1cc(NS(=O)(=O)c1cccs1)c(O)c2O | Homo sapiens | CHEMBL4666358 | single protein format |