P18440 | ARY1_HUMAN | Arylamine N-acetyltransferase 1 (NAT1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00797 | Acetyltransf_2 - N-acetyltransferase | 20~280 |
3D structures mapped by conservation among orthologs
[ Domain: "Cysteine proteinases" // Acetyltransf_2 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3262086 |  |
IC50 | = | 120.0 | nM | 419.46 | Nc1cccc2c1C(=O)C(NS(=O)(=O)c1ccccc1)=C(Nc1ccccc1)C2=O | Homo sapiens | CHEMBL3267122 | single protein format |
| CHEMBL458614 |  |
IC50 | = | 330.0 | nM | 489.1 | O=C1NC(=S)S/C1=C\c1cc(I)c(O)c(I)c1 | Homo sapiens | CHEMBL942267 | single protein format |
| CHEMBL3262085 |  |
IC50 | = | 540.0 | nM | 447.52 | Cc1cc(C)cc(NC2=C(NS(=O)(=O)c3ccccc3)C(=O)c3c(N)cccc3C2=O)c1 | Homo sapiens | CHEMBL3267122 | single protein format |
| CHEMBL457919 |  |
IC50 | = | 600.0 | nM | 237.31 | O=C1NC(=S)S/C1=C\c1cccc(O)c1 | Homo sapiens | CHEMBL942267 | single protein format |
| CHEMBL3262049 |  |
IC50 | = | 900.0 | nM | 483.34 | O=C1C(Nc2ccc(Br)cc2)=C(NS(=O)(=O)c2ccccc2)C(=O)c2ccccc21 | Homo sapiens | CHEMBL3267122 | single protein format |