P17936 | IBP3_HUMAN | Insulin-like growth factor-binding protein 3 (IGFBP3)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00086 | Thyroglobulin_1 - Thyroglobulin type-1 repeat | 213~285 | |
| PF00219 | IGFBP - Insulin-like growth factor binding protein | 40~94 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL292700 |  |
Ki | = | 5.6 | nM | 341.27 | O=C(O)c1cc2cc(O)c(O)cc2c(C(=O)c2ccc(O)c(O)c2)n1 | Homo sapiens | CHEMBL698360 | single protein format |
| CHEMBL58396 |  |
Ki | = | 7.5 | nM | 327.29 | O=C(O)c1cc2cc(O)c(O)cc2c(Cc2ccc(O)c(O)c2)n1 | Homo sapiens | CHEMBL698360 | single protein format |
| CHEMBL56978 |  |
Ki | = | 8.0 | nM | 327.29 | O=C(O)c1cc(Cc2ccc(O)c(O)c2)c2cc(O)c(O)cc2n1 | Homo sapiens | CHEMBL698358 | single protein format |
| CHEMBL292841 |  |
Ki | = | 9.0 | nM | 488.25 | O=C(O)c1cc2cc(O)c(O)cc2c(C(=O)c2ccc(Oc3cc(Cl)cc(Cl)c3)c(F)c2)n1 | Homo sapiens | CHEMBL698359 | single protein format |
| CHEMBL56740 |  |
Ki | = | 9.4 | nM | 433.39 | Cc1ccc(Oc2ccc(C(=O)c3nc(C(=O)O)cc4cc(O)c(O)cc34)cc2F)cc1 | Homo sapiens | CHEMBL698359 | single protein format |
| CHEMBL300828 |  |
Ki | = | 11.0 | nM | 453.81 | O=C(O)c1cc2cc(O)c(O)cc2c(C(=O)c2ccc(Oc3cccc(Cl)c3)c(F)c2)n1 | Homo sapiens | CHEMBL698359 | single protein format |
| CHEMBL294258 |  |
Ki | = | 11.0 | nM | 353.37 | Cc1cc(C)c(C(O)c2nc(C(=O)O)cc3cc(O)c(O)cc23)c(C)c1 | Homo sapiens | CHEMBL698359 | single protein format |
| CHEMBL292890 |  |
Ki | = | 12.0 | nM | 488.25 | O=C(O)c1cc2cc(O)c(O)cc2c(C(=O)c2ccc(Oc3ccc(Cl)c(Cl)c3)c(F)c2)n1 | Homo sapiens | CHEMBL698359 | single protein format |
| CHEMBL131104 |  |
Ki | = | 13.0 | nM | 359.34 | O=C(O)c1cc2cc(O)c(O)cc2c(C(=O)c2ccc3ccccc3c2)n1 | Homo sapiens | CHEMBL698360 | single protein format |
| CHEMBL61192 |  |
Ki | = | 18.0 | nM | 379.29 | O=C(O)c1cc2cc(O)c(O)cc2c(C(O)c2ccc(C(F)(F)F)cc2)n1 | Homo sapiens | CHEMBL698359 | single protein format |
| CHEMBL57760 |  |
Ki | = | 20.0 | nM | 453.81 | O=C(O)c1cc2cc(O)c(O)cc2c(C(=O)c2ccc(Oc3ccc(Cl)cc3)c(F)c2)n1 | Homo sapiens | CHEMBL698359 | single protein format |
| CHEMBL56720 |  |
Ki | = | 24.0 | nM | 329.28 | O=C(O)c1cc2cc(O)c(O)cc2c(C(O)c2cccc(F)c2)n1 | Homo sapiens | CHEMBL698359 | single protein format |
| CHEMBL56721 |  |
Ki | = | 25.0 | nM | 345.74 | O=C(O)c1cc2cc(O)c(O)cc2c(C(O)c2ccccc2Cl)n1 | Homo sapiens | CHEMBL698359 | single protein format |
| CHEMBL128554 |  |
Ki | = | 27.0 | nM | 359.34 | O=C(O)c1cc2cc(O)c(O)cc2c(C(=O)c2cccc3ccccc23)n1 | Homo sapiens | CHEMBL698360 | single protein format |
| CHEMBL130994 |  |
Ki | = | 28.0 | nM | 313.26 | O=C(c1ccc(O)c(O)c1)c1nc(O)cc2cc(O)c(O)cc12 | Homo sapiens | CHEMBL698360 | single protein format |
| CHEMBL301887 |  |
Ki | = | 29.0 | nM | 378.17 | O=C(O)c1cc2cc(O)c(O)cc2c(C(=O)c2ccc(Cl)c(Cl)c2)n1 | Homo sapiens | CHEMBL698359 | single protein format |
| CHEMBL336069 |  |
Ki | = | 29.0 | nM | 299.28 | Oc1cc2cc(O)c(O)cc2c(Cc2ccc(O)c(O)c2)n1 | Homo sapiens | CHEMBL698360 | single protein format |
| CHEMBL301447 |  |
Ki | = | 31.0 | nM | 469.88 | O=C(O)c1cc2cc(O)c(O)cc2c(C(=O)c2ccc(Sc3ccc(Cl)cc3)c(F)c2)n1 | Homo sapiens | CHEMBL698359 | single protein format |
| CHEMBL57742 |  |
Ki | = | 32.0 | nM | 354.27 | O=C(O)c1cc2cc(O)c(O)cc2c(C(=O)c2ccc([N+](=O)[O-])cc2)n1 | Homo sapiens | CHEMBL698359 | single protein format |
| CHEMBL57084 |  |
Ki | = | 32.0 | nM | 495.46 | O=C(O)c1cc2cc(O)c(O)cc2c(C(=O)c2ccc(Oc3ccc(-c4ccccc4)cc3)c(F)c2)n1 | Homo sapiens | CHEMBL698359 | single protein format |