P17538 | CTRB1_HUMAN | Chymotrypsinogen B (CTRB1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00089 | Trypsin - Trypsin | 34~256 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL335675 |  |
IC50 | = | 5.3 | nM | 536.71 | CCCCC(NC(=O)c1ccccc1)C(C)(C)C(=O)OC(=O)C(C)(C)C(CCCC)NC(=O)c1ccccc1 | Homo sapiens | CHEMBL818539 | single protein format |
| CHEMBL436591 |  |
IC50 | = | 12.0 | nM | 564.77 | CCCC(=O)NC(CCc1ccccc1)C(C)(C)C(=O)OC(=O)C(C)(C)C(CCc1ccccc1)NC(=O)CCC | Homo sapiens | CHEMBL818539 | single protein format |
| CHEMBL2409452 |  |
IC50 | = | 15.0 | nM | 339.31 | COC(=O)c1nn(C(=O)c2cccc(C)c2)c2ccc([N+](=O)[O-])cc12 | Homo sapiens | CHEMBL2412036 | single protein format |
| CHEMBL2409457 |  |
IC50 | = | 21.0 | nM | 369.33 | CCOC(=O)c1nn(C(=O)c2cccc(OC)c2)c2ccc([N+](=O)[O-])cc12 | Homo sapiens | CHEMBL2412036 | single protein format |
| CHEMBL2409451 |  |
IC50 | = | 31.0 | nM | 325.28 | COC(=O)c1nn(C(=O)c2ccccc2)c2ccc([N+](=O)[O-])cc12 | Homo sapiens | CHEMBL2412036 | single protein format |
| CHEMBL424453 |  |
IC50 | = | 31.0 | nM | 564.77 | CCCCCC(NC(=O)c1ccccc1)C(C)(C)C(=O)OC(=O)C(C)(C)C(CCCCC)NC(=O)c1ccccc1 | Homo sapiens | CHEMBL818539 | single protein format |
| CHEMBL2409445 |  |
IC50 | = | 38.0 | nM | 339.31 | COC(=O)c1nn(C(=O)c2cccc(C)c2)c2cc([N+](=O)[O-])ccc12 | Homo sapiens | CHEMBL2412036 | single protein format |
| CHEMBL2409456 |  |
IC50 | = | 40.0 | nM | 353.33 | CCOC(=O)c1nn(C(=O)c2cccc(C)c2)c2ccc([N+](=O)[O-])cc12 | Homo sapiens | CHEMBL2412036 | single protein format |
| CHEMBL135080 |  |
IC50 | = | 44.0 | nM | 592.82 | CCCCCCC(NC(=O)c1ccccc1)C(C)(C)C(=O)OC(=O)C(C)(C)C(CCCCCC)NC(=O)c1ccccc1 | Homo sapiens | CHEMBL818539 | single protein format |
| CHEMBL2409458 |  |
IC50 | = | 46.0 | nM | 345.34 | CCOC(=O)c1nn(C(=O)c2ccsc2)c2ccc([N+](=O)[O-])cc12 | Homo sapiens | CHEMBL2412036 | single protein format |
| CHEMBL131704 |  |
IC50 | = | 49.0 | nM | 508.66 | CCCC(NC(=O)c1ccccc1)C(C)(C)C(=O)OC(=O)C(C)(C)C(CCC)NC(=O)c1ccccc1 | Homo sapiens | CHEMBL818539 | single protein format |
| CHEMBL294771 |  |
IC50 | = | 65.0 | nM | 323.4 | Cc1c(N(C)C)ccc2nc(N[C@H](C)c3ccccc3)oc(=O)c12 | Homo sapiens | CHEMBL656928 | single protein format |
| CHEMBL2409450 |  |
IC50 | = | 66.0 | nM | 261.28 | Cc1cccc(C(=O)n2nc(C#N)c3ccccc32)c1 | Homo sapiens | CHEMBL2412036 | single protein format |
| CHEMBL134068 |  |
IC50 | = | 72.0 | nM | 480.61 | CCC(NC(=O)c1ccccc1)C(C)(C)C(=O)OC(=O)C(C)(C)C(CC)NC(=O)c1ccccc1 | Homo sapiens | CHEMBL818539 | single protein format |
| CHEMBL65148 |  |
IC50 | = | 88.0 | nM | 280.33 | Cc1cccc2nc(N[C@H](C)c3ccccc3)oc(=O)c12 | Homo sapiens | CHEMBL656928 | single protein format |
| CHEMBL134268 |  |
IC50 | = | 140.0 | nM | 424.5 | CC(C)(CNC(=O)c1ccccc1)C(=O)OC(=O)C(C)(C)CNC(=O)c1ccccc1 | Homo sapiens | CHEMBL818539 | single protein format |
| CHEMBL2409571 |  |
IC50 | = | 140.0 | nM | 379.42 | CCOC(=O)c1nn(C(=O)c2cccc(C)c2)c2ccc(NC(=O)CC)cc12 | Homo sapiens | CHEMBL2412036 | single protein format |
| CHEMBL65589 |  |
IC50 | = | 140.0 | nM | 359.22 | Cc1cccc2nc(N[C@H](C)c3ccc(Br)cc3)oc(=O)c12 | Homo sapiens | CHEMBL656928 | single protein format |
| CHEMBL2409570 |  |
IC50 | = | 170.0 | nM | 365.39 | CCOC(=O)c1nn(C(=O)c2cccc(C)c2)c2ccc(NC(C)=O)cc12 | Homo sapiens | CHEMBL2412036 | single protein format |
| CHEMBL67023 |  |
IC50 | = | 180.0 | nM | 280.33 | Cc1cccc2nc(N[C@@H](C)c3ccccc3)oc(=O)c12 | Homo sapiens | CHEMBL656928 | single protein format |