P16444 | DPEP1_HUMAN | Dipeptidase 1 (DPEP1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF01244 | Peptidase_M19 - Membrane dipeptidase (Peptidase family M19) | 26~351 |
3D structures mapped by conservation among orthologs
[ Domain: "TIM barrels" // Peptidase_M19 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL119723 |  |
IC50 | = | 5.0 | nM | 369.37 | NC(CC1CCCCC1)P(=O)(O)C/C(=C\c1ccc(F)cc1)C(=O)O | Homo sapiens | CHEMBL801733 | single protein format |
| CHEMBL117337 |  |
IC50 | = | 6.0 | nM | 430.28 | NC(CC1CCCCC1)P(=O)(O)C/C(=C\c1ccc(Br)cc1)C(=O)O | Homo sapiens | CHEMBL801733 | single protein format |
| CHEMBL326292 |  |
IC50 | = | 8.0 | nM | 477.28 | NC(CC1CCCCC1)P(=O)(O)C/C(=C\c1ccc(I)cc1)C(=O)O | Homo sapiens | CHEMBL801733 | single protein format |
| CHEMBL333841 |  |
IC50 | = | 10.0 | nM | 419.38 | NC(CC1CCCCC1)P(=O)(O)C/C(=C\c1ccc(C(F)(F)F)cc1)C(=O)O | Homo sapiens | CHEMBL801733 | single protein format |
| CHEMBL119055 |  |
IC50 | = | 15.0 | nM | 369.37 | NC(CC1CCCCC1)P(=O)(O)C/C(=C/c1ccc(F)cc1)C(=O)O | Homo sapiens | CHEMBL801733 | single protein format |
| CHEMBL332970 |  |
IC50 | = | 20.0 | nM | 420.27 | NC(CC1CCCCC1)P(=O)(O)C/C(=C\c1ccc(Cl)c(Cl)c1)C(=O)O | Homo sapiens | CHEMBL801733 | single protein format |
| CHEMBL334279 |  |
IC50 | = | 25.0 | nM | 477.28 | NC(CC1CCCCC1)P(=O)(O)C/C(=C/c1ccc(I)cc1)C(=O)O | Homo sapiens | CHEMBL801733 | single protein format |
| CHEMBL120600 |  |
IC50 | = | 30.0 | nM | 430.28 | NC(CC1CCCCC1)P(=O)(O)C/C(=C/c1ccc(Br)cc1)C(=O)O | Homo sapiens | CHEMBL801733 | single protein format |
| CHEMBL334143 |  |
IC50 | = | 30.0 | nM | 403.82 | NC(CC1CCCCC1)P(=O)(O)C/C(=C\c1ccc(F)c(Cl)c1)C(=O)O | Homo sapiens | CHEMBL801733 | single protein format |
| CHEMBL332290 |  |
IC50 | = | 40.0 | nM | 448.27 | NC(CC1CCCCC1)P(=O)(O)C/C(=C\c1ccc(F)c(Br)c1)C(=O)O | Homo sapiens | CHEMBL801733 | single protein format |
| CHEMBL122415 |  |
IC50 | = | 45.0 | nM | 477.28 | NC(CC1CCCCC1)P(=O)(O)C/C(=C\c1cccc(I)c1)C(=O)O | Homo sapiens | CHEMBL801733 | single protein format |
| CHEMBL119261 |  |
IC50 | = | 70.0 | nM | 366.4 | Nc1ccc(/C=C(\CP(=O)(O)C(N)CC2CCCCC2)C(=O)O)cc1 | Homo sapiens | CHEMBL801733 | single protein format |
| CHEMBL325021 |  |
IC50 | = | 100.0 | nM | 477.28 | NC(CC1CCCCC1)P(=O)(O)C/C(=C\c1ccccc1I)C(=O)O | Homo sapiens | CHEMBL801733 | single protein format |
| CHEMBL120198 |  |
IC50 | = | 150.0 | nM | 366.4 | Nc1ccc(/C=C(/CP(=O)(O)C(N)CC2CCCCC2)C(=O)O)cc1 | Homo sapiens | CHEMBL801733 | single protein format |
| CHEMBL119118 |  |
IC50 | = | 200.0 | nM | 420.27 | NC(CC1CCCCC1)P(=O)(O)C/C(=C/c1ccc(Cl)c(Cl)c1)C(=O)O | Homo sapiens | CHEMBL801733 | single protein format |
| CHEMBL420537 |  |
IC50 | = | 200.0 | nM | 419.38 | NC(CC1CCCCC1)P(=O)(O)C/C(=C/c1ccc(C(F)(F)F)cc1)C(=O)O | Homo sapiens | CHEMBL801733 | single protein format |
| CHEMBL118190 |  |
IC50 | = | 250.0 | nM | 477.28 | NC(CC1CCCCC1)P(=O)(O)C/C(=C/c1cccc(I)c1)C(=O)O | Homo sapiens | CHEMBL801733 | single protein format |
| CHEMBL119392 |  |
IC50 | = | 350.0 | nM | 403.82 | NC(CC1CCCCC1)P(=O)(O)C/C(=C/c1ccc(F)c(Cl)c1)C(=O)O | Homo sapiens | CHEMBL801733 | single protein format |
| CHEMBL331554 |  |
IC50 | = | 1000.0 | nM | 477.28 | NC(CC1CCCCC1)P(=O)(O)C/C(=C/c1ccccc1I)C(=O)O | Homo sapiens | CHEMBL801733 | single protein format |