3D structures mapped by conservation among orthologs

[ Domain: "Lipase/lipooxygenase domain (PLAT/LH2 domain)" // PLAT ]

 PyMOL session

[ Domain: "alpha/beta-Hydrolases" // Lipase ]

 PyMOL session

[ Alpha Fold Model ] (go)

Known binders annotated in ChEMBL

 IC50 CSV

Only the first 20 rows are shown.

molecule_chembl_id	structure	assay_type	relation	value	unit	mol_wt	smiles	organism	assay_chembl_id	bao_label
CHEMBL175247		IC50	=	190.0	nM	495.75	CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)[C@H](CC(C)C)NC=O	Homo sapiens	CHEMBL4151255	single protein format
CHEMBL470029		IC50	=	490.0	nM	454.7	CC1(C)CC[C@]2(C(=O)O)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CCC(=O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]2C1	Homo sapiens	CHEMBL5328241	single protein format