P16083 | NQO2_HUMAN | Ribosyldihydronicotinamide dehydrogenase [quinone] (NQO2)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF02525 | Flavodoxin_2 - Flavodoxin-like fold | 4~212 |
3D structures mapped by conservation among orthologs
[ Domain: "Flavoproteins" // FMN_red ]
- 1QR2
- 1SG0
- 1XI2
- 1ZX1
- 2BZS
- 2QMY
- 2QMZ
- 2QR2
- 2QWX
- 2QX4
- 2QX6
- 2QX8
- 2QX9
- 3FW1
- 3G5M
- 3GAM
- 3NFR
- 3NHF
- 3NHJ
- 3NHK
- 3NHL
- 3NHP
- 3NHR
- 3NHS
- 3NHU
- 3NHW
- 3NHY
- 3O2N
- 3O73
- 3OVM
- 3OWH
- 3OWX
- 3OX1
- 3OX2
- 3OX3
- 3TE7
- 3TEM
- 3TZB
- 3UXE
- 3UXH
- 4FGJ
- 4FGK
- 4FGL
- 4GQI
- 4GR9
- 4QOD
- 4QOE
- 4QOF
- 4QOG
- 4QOH
- 4QOI
- 4QOJ
- 4U7F
- 4U7G
- 4U7H
- 4XDG
- 4XDH
- 4ZVK
- 4ZVL
- 4ZVM
- 4ZVN
- 5BUC
- 5LBT
- 5LBU
- 5LBW
- 5LBY
- 5LBZ
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL1770214 |  |
IC50 | = | 0.39 | nM | 286.33 | COC(=O)Nc1ccc2cccc(CCNC(C)=O)c2c1 | Homo sapiens | CHEMBL1772363 | single protein format |
| CHEMBL1945729 |  |
IC50 | = | 4.1 | nM | 305.73 | CNc1c(Cl)c(N)c2c3c(cc(C(N)=O)nc13)C(=O)N2C | Homo sapiens | CHEMBL1948139 | single protein format |
| CHEMBL1738752 |  |
IC50 | = | 4.9 | nM | 306.39 | CNS(=O)(=O)c1ccc2cccc(CCNC(C)=O)c2c1 | Homo sapiens | CHEMBL1772363 | single protein format |
| CHEMBL8602 |  |
IC50 | = | 6.0 | nM | 410.47 | CCN(CC)CCNc1ccc2ncn3c4cc(OC)c(OC)c(O)c4c(=O)c1c23 | Homo sapiens | CHEMBL1109212 | single protein format |
| CHEMBL2 |  |
IC50 | = | 7.8 | nM | 383.41 | COc1cc2nc(N3CCN(C(=O)c4ccco4)CC3)nc(N)c2cc1OC | Homo sapiens | CHEMBL1772367 | single protein format |
| CHEMBL124254 |  |
IC50 | = | 9.0 | nM | 378.48 | CCN(CC)CCNc1ccc2nc(C)n3c4ccc(OC)cc4c(=O)c1c23 | Homo sapiens | CHEMBL1109212 | single protein format |
| CHEMBL457992 |  |
IC50 | = | 9.1 | nM | 358.42 | CNS(=O)(=O)c1ccc2cccc(CCNC(=O)c3ccco3)c2c1 | Homo sapiens | CHEMBL1772363 | single protein format |
| CHEMBL4514167 |  |
IC50 | = | 10.0 | nM | 292.34 | COc1ccc2nc(C)cc(N/N=C/c3cccnc3)c2c1 | Homo sapiens | CHEMBL4363871 | assay format |
| CHEMBL1967497 |  |
IC50 | = | 13.0 | nM | 337.38 | COc1ccc2nc(C)cc(N/N=C/c3cccc(OC)c3O)c2c1 | Homo sapiens | CHEMBL4363871 | assay format |
| CHEMBL1836819 |  |
IC50 | = | 14.0 | nM | 352.39 | COc1ccc2c(c1)c(=O)c1c(NCC[N+](C)(C)[O-])ccc3ncn2c31 | Homo sapiens | CHEMBL1837963 | single protein format |
| CHEMBL4435240 |  |
IC50 | = | 15.0 | nM | 305.38 | COc1ccc2nc(C)cc(N/N=C/Cc3ccccc3)c2c1 | Homo sapiens | CHEMBL4363871 | assay format |
| CHEMBL125082 |  |
IC50 | = | 16.0 | nM | 364.45 | CCN(CC)CCNc1ccc2nc(C)n3c4ccc(O)cc4c(=O)c1c23 | Homo sapiens | CHEMBL1109212 | single protein format |
| CHEMBL8150 |  |
IC50 | = | 17.0 | nM | 394.48 | CCN(CC)CCNc1ccc2ncn3c4c(OC)ccc(OC)c4c(=O)c1c23 | Homo sapiens | CHEMBL1109212 | single protein format |
| CHEMBL1237241 |  |
IC50 | = | 18.0 | nM | 326.31 | COc1ccc2nc(C)cc(N/N=C/c3ccc([N+](=O)[O-])o3)c2c1 | Homo sapiens | CHEMBL4363871 | assay format |
| CHEMBL456727 |  |
IC50 | = | 18.0 | nM | 259.37 | CSc1ccc2cccc(CCNC(C)=O)c2c1 | Homo sapiens | CHEMBL1772363 | single protein format |
| CHEMBL458209 |  |
IC50 | = | 21.0 | nM | 291.37 | CC(=O)NCCc1cccc2ccc(S(C)(=O)=O)cc12 | Homo sapiens | CHEMBL1772363 | single protein format |
| CHEMBL3770366 |  |
IC50 | = | 24.0 | nM | 367.36 | CC(=O)O.N=C(N)c1ccc(-c2ccc(-c3ccc([N+](=O)[O-])cc3)o2)cc1 | Homo sapiens | CHEMBL3771536 | single protein format |
| CHEMBL3770674 |  |
IC50 | = | 28.0 | nM | 367.36 | CC(=O)O.N=C(N)c1ccc(-c2ccc(-c3cccc([N+](=O)[O-])c3)o2)cc1 | Homo sapiens | CHEMBL3771536 | single protein format |
| CHEMBL8219 |  |
IC50 | = | 31.0 | nM | 380.45 | CCN(CC)CCNc1ccc2ncn3c4c(OC)ccc(O)c4c(=O)c1c23 | Homo sapiens | CHEMBL1109212 | single protein format |
| CHEMBL457763 |  |
IC50 | = | 32.0 | nM | 292.36 | CC(=O)NCCc1cccc2ccc(S(N)(=O)=O)cc12 | Homo sapiens | CHEMBL1772363 | single protein format |