P15735 | PHKG2_HUMAN | Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHKG2)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00069 | Pkinase - Protein kinase domain | 25~291 |
3D structures mapped by conservation among orthologs
[ Domain: "Protein kinase" // Pkinase_Tyr ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL388978 |  |
IC50 | = | 0.49 | nM | 466.54 | CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 | Homo sapiens | CHEMBL4145890 | single protein format |
| CHEMBL2151321 |  |
IC50 | = | 6.1 | nM | 381.42 | CC(C)Oc1cc(-n2cnc3ccc(N[C@@H](C)c4ccc(F)cn4)nc32)n[nH]1 | Homo sapiens | CHEMBL2154707 | single protein format |
| CHEMBL3979920 |  |
IC50 | = | 226.0 | nM | 344.39 | Cn1cc(-c2nc(N[C@@H]3CCCC[C@@H]3N)c(F)c3c2C(=O)NC3)cn1 | Homo sapiens | CHEMBL3869734 | assay format |
| CHEMBL1231206 |  |
IC50 | = | 528.0 | nM | 374.47 | Cc1ccc(-c2ccc3c(ccc4sc5c(c43)NC[C@@H](C)NC5=O)n2)cn1 | Homo sapiens | CHEMBL5212750 | single protein format |
| CHEMBL3288854 |  |
Ki | = | 840.0 | nM | 425.51 | Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1NC(=O)CCN1CCN(C)CC1 | Homo sapiens | CHEMBL3296773 | single protein format |