P15559 | NQO1_HUMAN | NAD(P)H dehydrogenase [quinone] 1 (NQO1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF02525 | Flavodoxin_2 - Flavodoxin-like fold | 5~211 |
3D structures mapped by conservation among orthologs
[ Domain: "Flavoproteins" // FMN_red ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL570570 |  |
IC50 | = | 0.18 | nM | 444.48 | O=c1oc2c3c(ccc2c(O)c1Cc1c(O)c2ccc4c(c2oc1=O)CCCC4)CCCC3 | Homo sapiens | CHEMBL1045769 | single protein format |
| CHEMBL571058 |  |
IC50 | = | 0.41 | nM | 392.41 | Cc1cc2oc(=O)c(Cc3c(O)c4cc(C)c(C)cc4oc3=O)c(O)c2cc1C | Homo sapiens | CHEMBL1045769 | single protein format |
| CHEMBL569640 |  |
IC50 | = | 0.42 | nM | 392.41 | Cc1ccc2c(O)c(Cc3c(O)c4ccc(C)c(C)c4oc3=O)c(=O)oc2c1C | Homo sapiens | CHEMBL1045769 | single protein format |
| CHEMBL569641 |  |
IC50 | = | 2.2 | nM | 356.42 | O=c1oc2c3c(ccc2c(O)c1Cc1ccc2ccccc2c1)CCCC3 | Homo sapiens | CHEMBL1045769 | single protein format |
| CHEMBL570349 |  |
IC50 | = | 2.5 | nM | 330.38 | Cc1cc2oc(=O)c(Cc3ccc4ccccc4c3)c(O)c2cc1C | Homo sapiens | CHEMBL1045769 | single protein format |
| CHEMBL571496 |  |
IC50 | = | 2.8 | nM | 396.35 | COc1cccc2oc(=O)c(Cc3c(O)c4c(OC)cccc4oc3=O)c(O)c12 | Homo sapiens | CHEMBL1045769 | single protein format |
| CHEMBL576293 |  |
IC50 | = | 3.8 | nM | 372.28 | O=c1oc2cc(F)ccc2c(O)c1Cc1c(O)c2ccc(F)cc2oc1=O | Homo sapiens | CHEMBL1045769 | single protein format |
| CHEMBL569406 |  |
IC50 | = | 4.5 | nM | 372.28 | O=c1oc2ccc(F)cc2c(O)c1Cc1c(O)c2cc(F)ccc2oc1=O | Homo sapiens | CHEMBL1045769 | single protein format |
| CHEMBL312727 |  |
IC50 | = | 5.0 | nM | 368.3 | O=c1c(Cc2c(O)oc3cc(O)ccc3c2=O)c(O)oc2cc(O)ccc12 | Homo sapiens | CHEMBL901432 | single protein format |
| CHEMBL576259 |  |
IC50 | = | 6.0 | nM | 356.42 | O=c1oc2ccc3c(c2c(O)c1Cc1ccc2ccccc2c1)CCCC3 | Homo sapiens | CHEMBL1045769 | single protein format |
| CHEMBL569627 |  |
IC50 | = | 6.0 | nM | 396.35 | COc1ccc2c(O)c(Cc3c(O)c4ccc(OC)cc4oc3=O)c(=O)oc2c1 | Homo sapiens | CHEMBL1045769 | single protein format |
| CHEMBL568962 |  |
IC50 | = | 6.3 | nM | 356.42 | O=c1oc2ccc3c(c2c(O)c1Cc1cccc2ccccc12)CCCC3 | Homo sapiens | CHEMBL1045769 | single protein format |
| CHEMBL571059 |  |
IC50 | = | 6.3 | nM | 356.42 | O=c1oc2c3c(ccc2c(O)c1Cc1cccc2ccccc12)CCCC3 | Homo sapiens | CHEMBL1045769 | single protein format |
| CHEMBL569169 |  |
IC50 | = | 7.7 | nM | 330.38 | Cc1cc2oc(=O)c(Cc3cccc4ccccc34)c(O)c2cc1C | Homo sapiens | CHEMBL1045769 | single protein format |
| CHEMBL572166 |  |
IC50 | = | 9.0 | nM | 405.19 | O=c1oc2ccc(Cl)cc2c(O)c1Cc1c(O)c2cc(Cl)ccc2oc1=O | Homo sapiens | CHEMBL1045769 | single protein format |
| CHEMBL571272 |  |
IC50 | = | 9.9 | nM | 308.38 | Cc1ccc(Cc2c(O)c3cc(C)c(C)cc3oc2=O)cc1C | Homo sapiens | CHEMBL1045769 | single protein format |
| CHEMBL583323 |  |
IC50 | = | 11.0 | nM | 396.35 | COc1ccc2oc(=O)c(Cc3c(O)c4cc(OC)ccc4oc3=O)c(O)c2c1 | Homo sapiens | CHEMBL1045769 | single protein format |
| CHEMBL569415 |  |
IC50 | = | 14.0 | nM | 364.35 | Cc1ccc2oc(=O)c(Cc3c(O)c4cc(C)ccc4oc3=O)c(O)c2c1 | Homo sapiens | CHEMBL1045769 | single protein format |
| CHEMBL571283 |  |
IC50 | = | 14.0 | nM | 302.33 | O=c1oc2ccccc2c(O)c1Cc1ccc2ccccc2c1 | Homo sapiens | CHEMBL1045769 | single protein format |
| CHEMBL573922 |  |
IC50 | = | 15.0 | nM | 306.36 | O=c1oc2ccc3c(c2c(O)c1Cc1ccccc1)CCCC3 | Homo sapiens | CHEMBL1045769 | single protein format |