P15090 | FABP4_HUMAN | Fatty acid-binding protein, adipocyte (FABP4)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00061 | Lipocalin - Lipocalin / cytosolic fatty-acid binding protein family | 6~131 |
3D structures mapped by conservation among orthologs
[ Domain: "Lipocalins" // Lipocalin_7 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3905766 |  |
IC50 | = | 10.0 | nM | 345.38 | O=C(O)C1=C(C(=O)Nc2sccc2-c2nc(C3CC3)no2)CCC1 | Homo sapiens | CHEMBL3888563 | single protein format |
| CHEMBL5281007 |  |
IC50 | = | 10.0 | nM | 388.52 | Cc1cc(-c2c3c(nc(C4(C)CCCC4)c2-c2nnn[nH]2)CCCCC3)ccn1 | Homo sapiens | CHEMBL5262837 | single protein format |
| CHEMBL5278127 |  |
IC50 | = | 10.0 | nM | 374.49 | Cc1cc(-c2c3c(nc(C4CCCC4)c2-c2nnn[nH]2)CCC(C)C3)ccn1 | Homo sapiens | CHEMBL5262837 | single protein format |
| CHEMBL3918729 |  |
IC50 | = | 10.0 | nM | 399.47 | Cc1c(C2CC2)sc(NC(=O)C2=C(C(=O)O)CCC2)c1-c1nc(C2CC2)no1 | Homo sapiens | CHEMBL3888563 | single protein format |
| CHEMBL3919426 |  |
IC50 | = | 10.0 | nM | 373.43 | Cc1sc(NC(=O)C2=C(C(=O)O)CCC2)c(-c2nc(C3CC3)no2)c1C | Homo sapiens | CHEMBL3888563 | single protein format |
| CHEMBL3896829 |  |
IC50 | = | 10.0 | nM | 427.4 | Cc1sc(NC(=O)C2=C(C(=O)O)CCC2)c(-c2nc(C(F)(F)F)no2)c1C1CC1 | Homo sapiens | CHEMBL3888563 | single protein format |
| CHEMBL3915309 |  |
IC50 | = | 11.0 | nM | 389.5 | Cc1sc(NC(=O)C2=C(C(=O)O)CCC2)c(-c2nc(C3CC3)ns2)c1C | Homo sapiens | CHEMBL3888563 | single protein format |
| CHEMBL3923099 |  |
IC50 | = | 13.0 | nM | 455.61 | Cc1c(C2CC2)sc(NC(=O)C2=C(C(=O)O)C3CCC2CC3)c1-c1nc(C2CC2)ns1 | Homo sapiens | CHEMBL3888563 | single protein format |
| CHEMBL5268944 |  |
IC50 | = | 13.0 | nM | 396.86 | CCN(CC)c1nc2cc(F)c(Cl)cc2c(-c2ccccc2)c1-c1nnn[nH]1 | Homo sapiens | CHEMBL5262831 | single protein format |
| CHEMBL5268623 |  |
IC50 | = | 13.0 | nM | 408.87 | Fc1cc2nc(N3CCCCC3)c(-c3nnn[nH]3)c(-c3ccccc3)c2cc1Cl | Homo sapiens | CHEMBL5262831 | single protein format |
| CHEMBL3914116 |  |
IC50 | = | 13.0 | nM | 415.54 | Cc1c(C2CC2)sc(NC(=O)C2=C(C(=O)O)CCC2)c1-c1nc(C2CC2)ns1 | Homo sapiens | CHEMBL3888563 | single protein format |
| CHEMBL3964149 |  |
IC50 | = | 15.0 | nM | 359.41 | Cc1csc(NC(=O)C2=C(C(=O)O)CCC2)c1-c1nc(C2CC2)no1 | Homo sapiens | CHEMBL3888563 | single protein format |
| CHEMBL5274115 |  |
IC50 | = | 17.0 | nM | 395.87 | CCC(CC)c1nc2cc(F)c(Cl)cc2c(-c2ccccc2)c1-c1nnn[nH]1 | Homo sapiens | CHEMBL5262831 | single protein format |
| CHEMBL3920664 |  |
IC50 | = | 19.0 | nM | 429.57 | Cc1c(C2CC2)sc(NC(=O)C2=C(C(=O)O)CCCC2)c1-c1nc(C2CC2)ns1 | Homo sapiens | CHEMBL3888563 | single protein format |
| CHEMBL3903803 |  |
IC50 | = | 19.2 | nM | 385.45 | O=C(O)C1=C(C(=O)Nc2scc(C3CC3)c2-c2nc(C3CC3)no2)CCC1 | Homo sapiens | CHEMBL3888563 | single protein format |
| CHEMBL3914622 |  |
IC50 | = | 20.0 | nM | 427.4 | Cc1sc(NC(=O)C2=C(C(=O)O)CCC2)c(-c2nc(C3CC3)no2)c1C(F)(F)F | Homo sapiens | CHEMBL3888563 | single protein format |
| CHEMBL3979971 |  |
IC50 | = | 20.0 | nM | 387.46 | Cc1sc(NC(=O)C2=C(C(=O)O)CCCC2)c(-c2nc(C3CC3)no2)c1C | Homo sapiens | CHEMBL3888563 | single protein format |
| CHEMBL3928329 |  |
IC50 | = | 20.0 | nM | 359.41 | Cc1cc(-c2nc(C3CC3)no2)c(NC(=O)C2=C(C(=O)O)CCC2)s1 | Homo sapiens | CHEMBL3888563 | single protein format |
| CHEMBL3896498 |  |
IC50 | = | 20.0 | nM | 399.47 | Cc1sc(NC(=O)C2=C(C(=O)O)CCC2)c(-c2nc(C3CC3)no2)c1C1CC1 | Homo sapiens | CHEMBL3888563 | single protein format |
| CHEMBL3967672 |  |
IC50 | = | 20.0 | nM | 439.54 | Cc1sc(NC(=O)C2=C(C(=O)O)C3CCC2CC3)c(-c2nc(C3CC3)no2)c1C1CC1 | Homo sapiens | CHEMBL3888563 | single protein format |