P14920 | OXDA_HUMAN | D-amino-acid oxidase (DAO)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF01266 | DAO - FAD dependent oxidoreductase | 2~329 |
3D structures mapped by conservation among orthologs
[ Domain: "FAD-linked reductases-C" // DAO_2nd ]
[ Domain: "Nucleotide-binding domain" // DAO_1st ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3904227 |  |
IC50 | = | 1.2 | nM | 292.34 | O=c1[nH]nc(CCc2ccc(-c3ccccc3)cc2)cc1O | Homo sapiens | CHEMBL3887715 | assay format |
| CHEMBL3965781 |  |
IC50 | = | 2.1 | nM | 246.27 | O=c1[nH]nc(CCc2cccc(CO)c2)cc1O | Homo sapiens | CHEMBL3887715 | assay format |
| CHEMBL3925924 |  |
IC50 | = | 2.2 | nM | 252.22 | O=c1[nH]nc(CCc2ccc(F)cc2F)cc1O | Homo sapiens | CHEMBL3887715 | assay format |
| CHEMBL3899415 |  |
IC50 | = | 2.3 | nM | 236.2 | O=c1cc(COc2cccc(F)c2)[nH]nc1O | Homo sapiens | CHEMBL3887715 | assay format |
| CHEMBL3941866 |  |
IC50 | = | 2.3 | nM | 266.3 | O=c1[nH]nc(CCc2cccc3ccccc23)cc1O | Homo sapiens | CHEMBL3887715 | assay format |
| CHEMBL2338786 |  |
IC50 | = | 2.4 | nM | 216.24 | O=c1[nH]nc(CCc2ccccc2)cc1O | Homo sapiens | CHEMBL2343132 | cell-based format |
| CHEMBL3913880 |  |
IC50 | = | 2.5 | nM | 244.29 | O=c1[nH]nc(CCCCc2ccccc2)cc1O | Homo sapiens | CHEMBL3887715 | assay format |
| CHEMBL3985690 |  |
IC50 | = | 2.5 | nM | 230.27 | Cc1cccc(CCc2cc(O)c(=O)[nH]n2)c1 | Homo sapiens | CHEMBL3887715 | assay format |
| CHEMBL3950593 |  |
IC50 | = | 2.9 | nM | 236.2 | O=c1cc(COc2ccc(F)cc2)[nH]nc1O | Homo sapiens | CHEMBL3887715 | assay format |
| CHEMBL3964892 |  |
IC50 | = | 2.9 | nM | 246.27 | O=c1[nH]nc(CCc2ccc(CO)cc2)cc1O | Homo sapiens | CHEMBL3887715 | assay format |
| CHEMBL467661 |  |
IC50 | = | 3.0 | nM | 214.58 | O=c1[nH]c2ncc(F)c(Cl)c2cc1O | Homo sapiens | CHEMBL938999 | cell-based format |
| CHEMBL494235 |  |
IC50 | = | 3.0 | nM | 179.15 | O=c1[nH]c2c(F)cccc2cc1O | Homo sapiens | CHEMBL938999 | cell-based format |
| CHEMBL3948236 |  |
IC50 | = | 3.3 | nM | 230.27 | Cc1ccccc1CCc1cc(O)c(=O)[nH]n1 | Homo sapiens | CHEMBL3887715 | assay format |
| CHEMBL3914284 |  |
IC50 | = | 3.5 | nM | 236.2 | O=c1cc(COc2ccccc2F)[nH]nc1O | Homo sapiens | CHEMBL3887715 | assay format |
| CHEMBL3930320 |  |
IC50 | = | 3.7 | nM | 268.73 | O=c1[nH]nc(SCc2ccc(Cl)cc2)cc1O | Homo sapiens | CHEMBL3888090 | single protein format |
| CHEMBL3900453 |  |
IC50 | = | 3.8 | nM | 214.22 | O=c1cc(/C=C/c2ccccc2)[nH]nc1O | Homo sapiens | CHEMBL3887715 | assay format |
| CHEMBL146227 |  |
IC50 | = | 4.0 | nM | 161.16 | O=c1[nH]c2ccccc2cc1O | Homo sapiens | CHEMBL938999 | cell-based format |
| CHEMBL495187 |  |
IC50 | = | 4.0 | nM | 195.6 | O=c1[nH]c2cccc(Cl)c2cc1O | Homo sapiens | CHEMBL938999 | cell-based format |
| CHEMBL2338795 |  |
IC50 | = | 4.4 | nM | 234.23 | O=c1[nH]nc(CCc2ccccc2F)cc1O | Homo sapiens | CHEMBL2343132 | cell-based format |
| CHEMBL467660 |  |
IC50 | = | 5.0 | nM | 213.59 | O=c1[nH]c2ccc(F)c(Cl)c2cc1O | Homo sapiens | CHEMBL938999 | cell-based format |