P14778 | IL1R1_HUMAN | Interleukin-1 receptor type 1 (IL1R1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF01582 | TIR - TIR domain | 387~549 | |
| PF13895 | Ig_2 - Immunoglobulin domain | 137~207 | |
| PF18452 | Ig_6 - Immunoglobulin domain | 40~108 |
3D structures mapped by conservation among orthologs
[ Domain: "Immunoglobulin/Fibronectin type III/E set domains/PapD-like" // I-set_4 ]
[ Domain: "Immunoglobulin/Fibronectin type III/E set domains/PapD-like" // I-set_5 ]
[ Domain: "Immunoglobulin/Fibronectin type III/E set domains/PapD-like" // I-set ]
[ Domain: "Immunoglobulin/Fibronectin type III/E set domains/PapD-like" // I-set_8 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4213787 |  |
IC50 | = | 720.0 | nM | 393.25 | O=C(NNC(=O)c1csc(-c2ccc(Cl)cc2Cl)n1)c1ccccn1 | Homo sapiens | CHEMBL4195489 | cell-based format |