P14672 | GLUT4_HUMAN | Solute carrier family 2, facilitated glucose transporter member 4 (SLC2A4)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00083 | Sugar_tr - Sugar (and other) transporter | 28~483 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4089982 |  |
IC50 | = | 90.0 | nM | 495.42 | COc1ccc(CC(=O)N[C@@H](Cc2ccccc2Br)C(=O)N[C@@H](C)c2ccccc2)cc1 | Homo sapiens | CHEMBL3992750 | cell-based format |
| CHEMBL4061928 |  |
IC50 | = | 195.0 | nM | 420.48 | C[C@H](NC(=O)[C@H](Cc1ccc(F)cc1)NC(=O)Cc1cccc(O)c1)c1ccccc1 | Homo sapiens | CHEMBL3992750 | cell-based format |
| CHEMBL4448899 |  |
IC50 | = | 270.0 | nM | 496.42 | Cc1c(NC(=O)c2cc(C(N)=O)nc3cc(F)ccc23)c(C(F)(F)F)nn1Cc1ccc(C#N)cc1 | Homo sapiens | CHEMBL4880934 | single protein format |
| CHEMBL4552180 |  |
IC50 | = | 500.0 | nM | 527.52 | Cc1c(NC(=O)c2cc(C(N)=O)nc3cc(F)ccc23)c(C(F)(F)F)nn1Cc1ccc(C(C)(C)C)cc1 | Homo sapiens | CHEMBL4880934 | single protein format |