P14598 | NCF1_HUMAN | Neutrophil cytosol factor 1 (NCF1)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00018 | SH3_1 | 162–207 | |
| PF00018 | SH3_1 | 232–277 | |
| PF00787 | PX | 31–120 | |
| PF08944 | p47_phox_C | 358–390 | |
| PF16621 | NCF1_PBR_AIR | 292–339 |
3D structures mapped by conservation among orthologs
[ Domain: "SH3" // SH3_1 ]
[ Domain: "SH3" // SH3_1_1 ]
[ Domain: "SH3" // SH3_1_1 ]
[ Domain: "PX domain" // PX ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL5410142 |  |
Ki | = | 240.0 | nM | 471.52 | Nc1ccc2cc(OCCOCCn3cc(COc4ccc5nc(N)ccc5c4)nn3)ccc2n1 | Homo sapiens | CHEMBL5374239 | assay format |
| CHEMBL5427803 |  |
Ki | = | 420.0 | nM | 389.46 | Nc1ccc2c(OCCNCCOc3cccc4nc(N)ccc34)cccc2n1 | Homo sapiens | CHEMBL5374239 | assay format |
| CHEMBL5411448 |  |
Ki | = | 440.0 | nM | 404.47 | Cc1cc(N)nc2cccc(OCCOCCOc3cccc4nc(N)ccc34)c12 | Homo sapiens | CHEMBL5374239 | assay format |
| CHEMBL5406295 |  |
Ki | = | 470.0 | nM | 418.5 | Cc1cc(N)nc2cccc(OCCOCCOc3cccc4nc(N)cc(C)c34)c12 | Homo sapiens | CHEMBL5374239 | assay format |
| CHEMBL5412642 |  |
Ki | = | 500.0 | nM | 455.52 | Nc1ccc2cc(OCCCCn3cc(COc4ccc5nc(N)ccc5c4)nn3)ccc2n1 | Homo sapiens | CHEMBL5374239 | assay format |
| CHEMBL5419067 |  |
Ki | = | 600.0 | nM | 390.44 | Nc1ccc2c(OCCOCCOc3cccc4nc(N)ccc34)cccc2n1 | Homo sapiens | CHEMBL5374239 | assay format |
| CHEMBL5410678 |  |
Ki | = | 640.0 | nM | 403.49 | CN(CCOc1cccc2nc(N)ccc12)CCOc1cccc2nc(N)ccc12 | Homo sapiens | CHEMBL5374239 | assay format |
| CHEMBL5413540 |  |
Ki | = | 680.0 | nM | 388.47 | Nc1ccc2c(OCCCCCOc3cccc4nc(N)ccc34)cccc2n1 | Homo sapiens | CHEMBL5374239 | assay format |
| CHEMBL5437628 |  |
Ki | = | 980.0 | nM | 404.47 | Cc1cc(OCCOCCOc2cccc3nc(N)ccc23)c2ccc(N)nc2c1 | Homo sapiens | CHEMBL5374239 | assay format |