P14210 | HGF_HUMAN | Hepatocyte growth factor (HGF)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00024 | PAN_1 | 42–123 | |
| PF00051 | Kringle | 128–206 | |
| PF00051 | Kringle | 211–288 | |
| PF00051 | Kringle | 305–383 | |
| PF00051 | Kringle | 391–469 | |
| PF00089 | Trypsin | 499–716 |
3D structures mapped by conservation among orthologs
[ Domain: "FMN-binding split barrel 2" // Trypsin_1 ]
[ Domain: "Kringle-like" // Kringle ]
[ Domain: "Hairpin loop containing domain-like" // PAN_1 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL461648 |  |
IC50 | = | 313.0 | nM | 497.53 | COc1cc2nccc(Oc3ccc(-c4cnc(Cc5ccccc5)n(C)c4=O)cc3F)c2cc1OC | Homo sapiens | CHEMBL971823 | cell-based format |