P14174 | MIF_HUMAN | Macrophage migration inhibitory factor (MIF)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF01187 | MIF - Macrophage migration inhibitory factor (MIF) | 2~115 |
3D structures mapped by conservation among orthologs
[ Domain: "Tautomerase/MIF" // MIF ]
- 1CA7
- 1CGQ
- 1GCZ
- 1GD0
- 1GIF
- 1LJT
- 1MIF
- 1P1G
- 2OOH
- 2OOW
- 2OOZ
- 3B9S
- 3CE4
- 3DJH
- 3DJI
- 3HOF
- 3IJG
- 3IJJ
- 3JSF
- 3JSG
- 3JTU
- 3L5P
- 3L5R
- 3L5S
- 3L5T
- 3L5U
- 3L5V
- 3SMB
- 3SMC
- 3U18
- 3WNR
- 3WNS
- 3WNT
- 4ETG
- 4EUI
- 4EVG
- 4F2K
- 4GRN
- 4GRO
- 4GRP
- 4GRQ
- 4GRR
- 4GRU
- 4K9G
- 4OSF
- 4OYQ
- 4P01
- 4P0H
- 4PKK
- 4PKZ
- 4PLU
- 4TRF
- 4TRU
- 4WR8
- 4WRB
- 4XX7
- 4XX8
- 4Z15
- 4Z1T
- 4Z1U
- 5B4O
- 5BS9
- 5BSC
- 5BSI
- 5BSJ
- 5EIZ
- 5HVS
- 5HVT
- 5HVV
- 5J7P
- 5J7Q
- 5UMJ
- 5UMK
- 5UZY
- 5V70
- 5V73
- 5XEJ
- 6B1C
- 6B1K
- 6B2C
- 6BG6
- 6BG7
- 6CB5
- 6CBF
- 6CBG
- 6CBH
- 6FVE
- 6FVH
- 6PEG
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL1256233 |  |
IC50 | = | 7.5 | nM | 255.27 | Cc1ccc2c(c1)oc(=O)n2Cc1cccc(O)c1 | Homo sapiens | CHEMBL1259538 | single protein format |
| CHEMBL1255975 |  |
IC50 | = | 10.0 | nM | 255.27 | Cc1ccc2oc(=O)n(Cc3cccc(O)c3)c2c1 | Homo sapiens | CHEMBL1259538 | single protein format |
| CHEMBL13486 |  |
IC50 | = | 38.0 | nM | 270.24 | O=c1c(-c2ccc(O)c(O)c2)coc2cc(O)ccc12 | Homo sapiens | CHEMBL3804641 | assay format |
| CHEMBL1089054 |  |
IC50 | = | 38.0 | nM | 254.24 | O=c1c(-c2ccc(O)c(O)c2)coc2ccccc12 | Homo sapiens | CHEMBL1100106 | single protein format |
| CHEMBL1253380 |  |
IC50 | = | 50.0 | nM | 282.32 | O=C(Oc1ccc(-c2ccccc2)nn1)c1cccs1 | Homo sapiens | CHEMBL1252123 | single protein format |
| CHEMBL1253382 |  |
IC50 | = | 80.0 | nM | 251.31 | CCCCOC(=O)Sc1nc2ccccc2o1 | Homo sapiens | CHEMBL1252123 | single protein format |
| CHEMBL3797982 |  |
IC50 | = | 110.0 | nM | 226.24 | Oc1ccc(-c2cnc3ccccn23)cc1O | Homo sapiens | CHEMBL3804644 | single protein format |
| CHEMBL223198 |  |
IC50 | = | 130.0 | nM | 260.27 | COc1ccc(N/N=C/c2ccc(O)c(F)c2)cc1 | Homo sapiens | CHEMBL918061 | single protein format |
| CHEMBL223319 |  |
IC50 | = | 220.0 | nM | 276.72 | COc1ccc(N/N=C/c2ccc(O)c(Cl)c2)cc1 | Homo sapiens | CHEMBL918061 | single protein format |
| CHEMBL233248 |  |
IC50 | = | 250.0 | nM | 99.16 | C=CCN=C=S | Homo sapiens | CHEMBL3411011 | cell-based format |
| CHEMBL1253381 |  |
IC50 | = | 300.0 | nM | 236.32 | S=C(Nc1ccccc1)Nc1nncs1 | Homo sapiens | CHEMBL1252123 | single protein format |
| CHEMBL223266 |  |
IC50 | = | 330.0 | nM | 321.17 | COc1ccc(N/N=C/c2ccc(O)c(Br)c2)cc1 | Homo sapiens | CHEMBL918061 | single protein format |
| CHEMBL3797437 |  |
IC50 | = | 360.0 | nM | 381.35 | Oc1cc2c(cc1C(c1ccc(C(F)(F)F)cc1)N1CCOCC1)OCO2 | Homo sapiens | CHEMBL3804643 | single protein format |
| CHEMBL4203719 |  |
IC50 | = | 370.0 | nM | 348.43 | O=C(NC(=S)Nc1ccc(O)cc1)c1ccc(-c2ccccc2)cc1 | Homo sapiens | CHEMBL4199313 | single protein format |
| CHEMBL199691 |  |
IC50 | = | 400.0 | nM | 233.29 | Oc1ccc(CSc2ccncc2)cc1O | Homo sapiens | CHEMBL864628 | single protein format |
| CHEMBL3799453 |  |
IC50 | = | 410.0 | nM | 260.22 | O=C(O/N=C/c1ccc(O)c(F)c1)c1cccnc1 | Homo sapiens | CHEMBL3804644 | single protein format |
| CHEMBL4761710 |  |
IC50 | = | 470.0 | nM | 317.14 | O=c1oc2cc(O)ccc2cc1-c1ccc(Br)cc1 | Homo sapiens | CHEMBL4702212 | assay format |
| CHEMBL224086 |  |
IC50 | = | 480.0 | nM | 242.28 | COc1ccc(N/N=C/c2ccc(O)cc2)cc1 | Homo sapiens | CHEMBL918061 | single protein format |
| CHEMBL523238 |  |
IC50 | = | 500.0 | nM | 239.27 | Cc1ccc2oc(=O)n(Cc3ccccc3)c2c1 | Homo sapiens | CHEMBL1021636 | single protein format |
| CHEMBL554271 |  |
IC50 | = | 500.0 | nM | 354.34 | O=C1c2ccccc2C(=O)N1CCC1CC(c2ccc(O)c(F)c2)=NO1 | Homo sapiens | CHEMBL1054355 | cell-based format |