P13501 | CCL5_HUMAN | C-C motif chemokine 5 (CCL5)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00048 | IL8 - Small cytokines (intecrine/chemokine), interleukin-8 like | 32~88 |
3D structures mapped by conservation among orthologs
[ Domain: "IL8" // IL8 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL1270493 |  |
IC50 | = | 17.0 | nM | 529.65 | Cc1ncnc(C)c1C(=O)N1C[C@H]2CN(CCC(c3ccccc3)C3CCN(CC(F)(F)F)CC3)C[C@H]2C1 | Homo sapiens | CHEMBL1272914 | single protein format |
| CHEMBL1270595 |  |
IC50 | = | 22.0 | nM | 551.76 | Cc1ncnc(C)c1C(=O)N1C[C@H]2CN(CCC(c3ccccc3)C3CN(S(=O)(=O)C4CCCC4)C3)C[C@H]2C1 | Homo sapiens | CHEMBL1272914 | single protein format |
| CHEMBL1269384 |  |
IC50 | = | 23.0 | nM | 579.81 | Cc1ncnc(C)c1C(=O)N1C[C@H]2CN(CCC(c3ccccc3)C3CCN(S(=O)(=O)C4CCCC4)CC3)C[C@H]2C1 | Homo sapiens | CHEMBL1272914 | single protein format |
| CHEMBL1270101 |  |
IC50 | = | 23.0 | nM | 525.72 | Cc1ncnc(C)c1C(=O)N1C[C@H]2CN(CCC(c3ccccc3)C3CN(S(=O)(=O)C(C)C)C3)C[C@H]2C1 | Homo sapiens | CHEMBL1272914 | single protein format |
| CHEMBL1270798 |  |
IC50 | = | 25.0 | nM | 547.64 | Cc1ncnc(C)c1C(=O)N1C[C@H]2CN(CCC(c3cc(F)cc(F)c3)C3CCN(CC(F)F)CC3)C[C@H]2C1 | Homo sapiens | CHEMBL1272914 | single protein format |
| CHEMBL1270799 |  |
IC50 | = | 25.0 | nM | 539.75 | CCS(=O)(=O)N1CCC(C(CCN2C[C@@H]3CN(C(=O)c4c(C)ncnc4C)C[C@@H]3C2)c2ccccc2)CC1 | Homo sapiens | CHEMBL1272914 | single protein format |
| CHEMBL1270594 |  |
IC50 | = | 27.0 | nM | 511.66 | Cc1ncnc(C)c1C(=O)N1C[C@H]2CN(CCC(c3ccccc3)C3CCN(CC(F)F)CC3)C[C@H]2C1 | Homo sapiens | CHEMBL1272914 | single protein format |
| CHEMBL1270694 |  |
IC50 | = | 27.0 | nM | 551.76 | Cc1ncnc(C)c1C(=O)N1C[C@H]2CN(CCC(c3ccccc3)C3CCN(S(=O)(=O)C4CC4)CC3)C[C@H]2C1 | Homo sapiens | CHEMBL1272914 | single protein format |
| CHEMBL1271108 |  |
IC50 | = | 27.0 | nM | 541.71 | Cc1cc(=O)oc(C)c1C(=O)N1C[C@H]2CN(CCC(c3ccccc3)C3CCN(S(C)(=O)=O)CC3)C[C@H]2C1 | Homo sapiens | CHEMBL1272914 | single protein format |
| CHEMBL1271208 |  |
IC50 | = | 31.0 | nM | 549.74 | Cc1cc(C#N)nc(C)c1C(=O)N1C[C@H]2CN(CCC(c3ccccc3)C3CCN(S(C)(=O)=O)CC3)C[C@H]2C1 | Homo sapiens | CHEMBL1272914 | single protein format |
| CHEMBL1271107 |  |
IC50 | = | 32.0 | nM | 503.69 | CCC(=O)N1CCC(C(CCN2C[C@@H]3CN(C(=O)c4c(C)ncnc4C)C[C@@H]3C2)c2ccccc2)CC1 | Homo sapiens | CHEMBL1272914 | single protein format |
| CHEMBL1270901 |  |
IC50 | = | 34.0 | nM | 525.72 | Cc1ncnc(C)c1C(=O)N1C[C@H]2CN(CCC(c3ccccc3)C3CCN(S(C)(=O)=O)CC3)C[C@H]2C1 | Homo sapiens | CHEMBL1272914 | single protein format |
| CHEMBL1270401 |  |
IC50 | = | 35.0 | nM | 559.68 | Cc1ncnc(C)c1C(=O)N1C[C@H]2CN(CCC(c3cc(F)cc(F)c3)C3CN(S(=O)(=O)C4CC4)C3)C[C@H]2C1 | Homo sapiens | CHEMBL1272914 | single protein format |
| CHEMBL1270693 |  |
IC50 | = | 35.0 | nM | 529.65 | Cc1ncnc(C)c1C(=O)N1C[C@H]2CN(CCC(c3cccc(F)c3)C3CCN(CC(F)F)CC3)C[C@H]2C1 | Homo sapiens | CHEMBL1272914 | single protein format |
| CHEMBL1270303 |  |
IC50 | = | 39.0 | nM | 541.69 | Cc1ncnc(C)c1C(=O)N1C[C@H]2CN(CCC(c3cccc(F)c3)C3CN(S(=O)(=O)C4CC4)C3)C[C@H]2C1 | Homo sapiens | CHEMBL1272914 | single protein format |
| CHEMBL1270209 |  |
IC50 | = | 40.0 | nM | 523.7 | Cc1ncnc(C)c1C(=O)N1C[C@H]2CN(CCC(c3ccccc3)C3CN(S(=O)(=O)C4CC4)C3)C[C@H]2C1 | Homo sapiens | CHEMBL1272914 | single protein format |
| CHEMBL1269885 |  |
IC50 | = | 44.0 | nM | 543.71 | Cc1ncnc(C)c1C(=O)N1C[C@H]2CN(CCC(c3cccc(F)c3)C3CCN(S(C)(=O)=O)CC3)C[C@H]2C1 | Homo sapiens | CHEMBL1272914 | single protein format |
| CHEMBL1271000 |  |
IC50 | = | 47.0 | nM | 553.77 | Cc1ncnc(C)c1C(=O)N1C[C@H]2CN(CCC(c3ccccc3)C3CCN(S(=O)(=O)C(C)C)CC3)C[C@H]2C1 | Homo sapiens | CHEMBL1272914 | single protein format |
| CHEMBL1269383 |  |
IC50 | = | 48.0 | nM | 593.72 | Cc1ncnc(C)c1C(=O)N1C[C@H]2CN(CCC(c3ccccc3)C3CCN(S(=O)(=O)CC(F)(F)F)CC3)C[C@H]2C1 | Homo sapiens | CHEMBL1272914 | single protein format |
| CHEMBL1270494 |  |
IC50 | = | 52.0 | nM | 497.67 | Cc1ncnc(C)c1C(=O)N1C[C@H]2CN(CCC(c3ccccc3)C3CN(S(C)(=O)=O)C3)C[C@H]2C1 | Homo sapiens | CHEMBL1272914 | single protein format |