P12644 | BMP4_HUMAN | Bone morphogenetic protein 4 (BMP4)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00019 | TGF_beta - Transforming growth factor beta like domain | 307~407 | |
| PF00688 | TGFb_propeptide - TGF-beta propeptide | 52~275 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL513147 |  |
IC50 | = | 4.9 | nM | 406.49 | c1ccc2c(-c3cnn4cc(-c5ccc(N6CCNCC6)cc5)cnc34)ccnc2c1 | Homo sapiens | CHEMBL989154 | single protein format |
| CHEMBL467972 |  |
IC50 | = | 5.0 | nM | 405.51 | c1ccc2c(-c3cnn4cc(-c5ccc(N6CCNCC6)cc5)ccc34)ccnc2c1 | Homo sapiens | CHEMBL989154 | single protein format |
| CHEMBL469053 |  |
IC50 | = | 10.0 | nM | 464.57 | CN1CCN(CCOc2ccc(-c3cnc4c(-c5ccnc6ccccc56)cnn4c3)cc2)CC1 | Homo sapiens | CHEMBL989154 | single protein format |
| CHEMBL511563 |  |
IC50 | = | 55.0 | nM | 352.4 | COc1ccc(-c2cnc3c(-c4ccnc5ccccc45)cnn3c2)cc1 | Homo sapiens | CHEMBL989154 | single protein format |
| CHEMBL469054 |  |
IC50 | = | 90.0 | nM | 449.56 | c1ccc2c(-c3cnn4cc(-c5ccc(OCCN6CCCCC6)cc5)cnc34)ccnc2c1 | Homo sapiens | CHEMBL989154 | single protein format |
| CHEMBL467560 |  |
IC50 | = | 150.0 | nM | 351.41 | COc1ccc(-c2ccc3c(-c4ccnc5ccccc45)cnn3c2)cc1 | Homo sapiens | CHEMBL989154 | single protein format |
| CHEMBL467345 |  |
IC50 | = | 250.0 | nM | 338.37 | Oc1ccc(-c2cnc3c(-c4ccnc5ccccc45)cnn3c2)cc1 | Homo sapiens | CHEMBL989154 | single protein format |
| CHEMBL468399 |  |
IC50 | = | 350.0 | nM | 440.94 | Clc1ccc2c(-c3cnn4cc(-c5ccc(N6CCNCC6)cc5)cnc34)ccnc2c1 | Homo sapiens | CHEMBL989154 | single protein format |
| CHEMBL478629 |  |
IC50 | = | 430.0 | nM | 399.5 | c1cc(-c2cnn3cc(-c4ccc(OCCN5CCCCC5)cc4)cnc23)ccn1 | Homo sapiens | CHEMBL989154 | single protein format |
| CHEMBL466765 |  |
IC50 | = | 450.0 | nM | 414.51 | CN1CCN(CCOc2ccc(-c3cnc4c(-c5ccncc5)cnn4c3)cc2)CC1 | Homo sapiens | CHEMBL989154 | single protein format |
| CHEMBL511929 |  |
IC50 | = | 500.0 | nM | 386.84 | COc1ccc(-c2cnc3c(-c4ccnc5cc(Cl)ccc45)cnn3c2)cc1 | Homo sapiens | CHEMBL989154 | single protein format |
| CHEMBL511216 |  |
IC50 | = | 500.0 | nM | 387.49 | CCN(CC)CCOc1ccc(-c2cnc3c(-c4ccncc4)cnn3c2)cc1 | Homo sapiens | CHEMBL989154 | single protein format |
| CHEMBL469055 |  |
IC50 | = | 750.0 | nM | 322.37 | c1ccc(-c2cnc3c(-c4ccnc5ccccc45)cnn3c2)cc1 | Homo sapiens | CHEMBL989154 | single protein format |