P11413 | G6PD_HUMAN | Glucose-6-phosphate 1-dehydrogenase (G6PD)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00479 | G6PD_N - Glucose-6-phosphate dehydrogenase, NAD binding domain | 35~210 | |
| PF02781 | G6PD_C - Glucose-6-phosphate dehydrogenase, C-terminal domain | 212~503 |
3D structures mapped by conservation among orthologs
[ Domain: "Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain" // G6PD_C ]
[ Domain: "NAD(P)-binding Rossmann-fold domains" // G6PD_N ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL5177201 |  |
IC50 | = | 70.0 | nM | 284.34 | N#Cc1cc(Nc2ncc3c(n2)CCCCC3=O)cs1 | Homo sapiens | CHEMBL5121905 | single protein format |
| CHEMBL1521758 |  |
IC50 | = | 200.0 | nM | 327.41 | Cc1ccc(C)c(S(=O)(=O)Nc2ccc(O)c3ccccc23)c1 | Homo sapiens | CHEMBL5121904 | assay format |
| CHEMBL5207151 |  |
IC50 | = | 600.0 | nM | 469.95 | COc1cc(/C=C2\C(=O)N(c3nc(-c4ccc(Cl)cc4)cs3)N=C2C)cc(OC)c1OC | Homo sapiens | CHEMBL5121904 | assay format |
| CHEMBL2057971 |  |
IC50 | = | 900.0 | nM | 334.5 | C[C@]12CC[C@H](O)C[C@@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](C(=O)CO)CC[C@@H]12 | Homo sapiens | CHEMBL2061901 | cell-based format |
| CHEMBL2057293 |  |
IC50 | = | 1000.0 | nM | 360.54 | CCNC(=O)N[C@H]1CC[C@@]2(C)[C@@H](CC[C@@H]3[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]32)C1 | Homo sapiens | CHEMBL2061901 | cell-based format |