P11168 | GTR2_HUMAN | Solute carrier family 2, facilitated glucose transporter member 2 (SLC2A2)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00083 | Sugar_tr - Sugar (and other) transporter | 14~499 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3781913 |  |
IC50 | = | 21.0 | nM | 400.49 | COc1ccccc1N1CCCN(c2ncnc3c2cnn3-c2ccccc2)CC1 | Homo sapiens | CHEMBL3782731 | cell-based format |
| CHEMBL3781149 |  |
IC50 | = | 60.0 | nM | 372.43 | Oc1ccccc1N1CCN(c2ncnc3c2cnn3-c2ccccc2)CC1 | Homo sapiens | CHEMBL3782731 | cell-based format |
| CHEMBL3781331 |  |
IC50 | = | 100.0 | nM | 429.48 | COc1ccc(C(N)=O)cc1N1CCN(c2ncnc3c2cnn3-c2ccccc2)CC1 | Homo sapiens | CHEMBL3782731 | cell-based format |
| CHEMBL3780717 |  |
IC50 | = | 220.0 | nM | 381.44 | N#Cc1cccc(N2CCN(c3ncnc4c3cnn4-c3ccccc3)CC2)c1 | Homo sapiens | CHEMBL3782731 | cell-based format |
| CHEMBL3780372 |  |
IC50 | = | 510.0 | nM | 387.45 | COc1ccncc1N1CCN(c2ncnc3c2cnn3-c2ccccc2)CC1 | Homo sapiens | CHEMBL3782731 | cell-based format |
| CHEMBL3780756 |  |
IC50 | = | 600.0 | nM | 385.47 | COc1ccccc1N1CCN(c2ccnc3c2cnn3-c2ccccc2)CC1 | Homo sapiens | CHEMBL3782731 | cell-based format |
| CHEMBL3780470 |  |
IC50 | = | 880.0 | nM | 434.48 | COc1ccccc1N1CCN(c2ncnc3c2cnn3-c2cc(F)ccc2OC)CC1 | Homo sapiens | CHEMBL3782731 | cell-based format |
| CHEMBL3780772 |  |
IC50 | = | 900.0 | nM | 416.49 | COc1cccc(-n2ncc3c(N4CCN(c5ccccc5OC)CC4)ncnc32)c1 | Homo sapiens | CHEMBL3782731 | cell-based format |
| CHEMBL3781835 |  |
IC50 | = | 950.0 | nM | 387.45 | COc1cccnc1N1CCN(c2ncnc3c2cnn3-c2ccccc2)CC1 | Homo sapiens | CHEMBL3782731 | cell-based format |
| CHEMBL3781347 |  |
IC50 | = | 1000.0 | nM | 400.49 | COc1ccccc1N1CCN(c2ncnc3c2cnn3-c2ccccc2C)CC1 | Homo sapiens | CHEMBL3782731 | cell-based format |